Parkinson's disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions/Experiment 1/Signature 2

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Reviewed Marked as Reviewed by Peace Sandy on 2024-2-5

Curated date: 2022/01/22

Curator: Fcuevas3

Revision editor(s): Fcuevas3, Aiyshaaaa, Peace Sandy

Source: Figure 2 and Figure 3

Description: Boxplots of seven significantly changed species in PD vs. controls (FDR < 0.05). Significance levels were determined using multivariable semi-parametrical fractional regressions with the group variable (PD vs. control) as a predictor of interest, including age, gender, BMI, and technical variables (total read counts and sequencing run (batch)) as covariates. FDR, false discovery rate

Boxplots of eight significantly changed genera in PD vs. controls (FDR < 0.05). Significance levels were determined using multivariable semi-parametrical fractional regressions with the group variable (PD vs. control) as a predictor of interest, including age, gender, BMI, and technical variables (total read counts and sequencing run (batch)) as covariates. FDR, false discovery rate

Abundance in Group 1: decreased abundance in Participants with typical PD

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Roseburia intestinalis
Turicibacter
Turicibacter sanguinis

Revision editor(s): Fcuevas3, Aiyshaaaa, Peace Sandy