The Bacterial Gut Microbiota of Schoolchildren from High and Low Socioeconomic Status: A Study in an Urban Area of Makassar, Indonesia/Experiment 1
From BugSigDB
Reviewed Marked as Reviewed by Peace Sandy on 2024-1-22
Subjects
- Location of subjects
- Indonesia
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Gut microbiome measurement Gut microbiome measurement,gut microbiome measurement
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Children of low SES
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Children of high SES
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High SES school is located in the city centre and is considered of high status, with a majority of the parents working as high-skilled workers or professionals with higher education.
- Group 0 sample size Number of subjects in the control (unexposed) group
- 66
- Group 1 sample size Number of subjects in the case (exposed) group
- 74
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- NA
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- PERMANOVA
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- decreased
- Richness Number of species
- unchanged
Signature 1
Reviewed Marked as Reviewed by Peace Sandy on 2024-1-22
Source: Figure 1C.
Description: Figure 1C. Differential abundance of bacterial taxa between high and low SES children. Taxa with Benjamini–Hochberg corrected p-value below 0.05 are shown.
Abundance in Group 1: increased abundance in Children of high SES
| NCBI | Quality Control | Links |
|---|---|---|
| Erysipelotrichaceae | ||
| Ruminococcus | ||
| Lachnospira sp. | ||
| Fusicatenibacter | ||
| Blautia | ||
| Anaerostipes | ||
| Eubacterium | ||
| Atopobiaceae | ||
| Bifidobacteriaceae | ||
| Bifidobacterium |
Revision editor(s): Kaluifeanyi101, Peace Sandy
Signature 2
Reviewed Marked as Reviewed by Peace Sandy on 2024-1-22
Source: Figure 1C.
Description: Figure 1C. Differential abundance of bacterial taxa between high and low SES children. Taxa with Benjamini–Hochberg corrected p-value below 0.05 are shown.
Abundance in Group 1: decreased abundance in Children of high SES
Revision editor(s): Kaluifeanyi101, Peace Sandy
