The gut microbiota of Colombians differs from that of Americans, Europeans and Asians/Experiment 4

From BugSigDB


Reviewed Marked as Reviewed by Peace Sandy on 2024-2-19

Curated date: 2022/07/21

Curator: Kaluifeanyi101

Revision editor(s): Kaluifeanyi101, Peace Sandy

Subjects

Location of subjects
Colombia
Denmark
France
Japan
South Korea
Spain
United States of America
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Ethnic group Ethnicity,race,Ethnic group,ethnic group
Group 0 name Corresponds to the control (unexposed) group for case-control studies
USA data
Group 1 name Corresponds to the case (exposed) group for case-control studies
Japan data
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
The Japanese dataset consisted of 454-generated V1 and V2 16S rDNA sequences of 10 lean and one overweight adult (six females and five males) that participated in an intervention with probiotics
Group 0 sample size Number of subjects in the control (unexposed) group
54
Group 1 sample size Number of subjects in the case (exposed) group
11
Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
4 months

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V1-V2
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Roche454

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
PERMANOVA
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes
Confounders controlled for Confounding factors that have been accounted for by stratification or model adjustment
age, waist circumference, sex


Signature 1

Reviewed Marked as Reviewed by Peace Sandy on 2024-2-19

Curated date: 2022/07/21

Curator: Kaluifeanyi101

Revision editor(s): Kaluifeanyi101

Source: Table 2

Description: Taxonomic composition of the gut microbiota in the different datasets.

Data presented as average ± standard deviation; P-values from ANOVA testing differences among lean, overweight, and obese subjects. WC = waist circumference; NA = not available.

Abundance in Group 1: increased abundance in Japan data

NCBI Quality ControlLinks
Actinomycetota

Revision editor(s): Kaluifeanyi101

Signature 2

Reviewed Marked as Reviewed by Peace Sandy on 2024-2-19

Curated date: 2022/07/21

Curator: Kaluifeanyi101

Revision editor(s): Kaluifeanyi101, Peace Sandy

Source: Table 2

Description: Taxonomic composition of the gut microbiota in the different datasets

Data presented as average ± standard deviation; P-values from ANOVA testing differences among lean, overweight, and obese subjects. WC = waist circumference; NA = not available.

Abundance in Group 1: decreased abundance in Japan data

NCBI Quality ControlLinks
Bacillota

Revision editor(s): Kaluifeanyi101, Peace Sandy