14q32 duplication syndrome
From BugSigDB
14q32 duplication syndrome is a rare chromosomal anomaly syndrome resulting from the partial duplication of the long arm of chromosome 14 that results in a predisposition to a number of adult-onset myeloproliferative neoplasms, including acute myeloid leukemia, chronic myelomonocytic leukemia, and myeloproliferative neoplasms, especially essential thrombocythemia. Progression to myelofibrosis and secondary acute myeloid leukemia can be observed.
- Aliases
- chromosome 14q32 DUPLICATION syndrome, 700-KB
- dup(14)q(32)
- myeloproliferative neoplasms, familial, susceptibility to
- predisposition to adult-onset myeloproliferative neoplasm due to 14q32 duplication
- trisomy 14q32
