BugSigDB

A Comprehensive Database of Published Microbial Signatures

BugSigDB.org (published in Nature Biotechnology) is a community-editable Semantic Mediawiki knowledge management system. Its primary functions include 1. standardization of key elements of published microbiome studies using ontologies and the NCBI taxonomy, 2. searchability, 3. Enrichment Analysis using bulk exports, GMT files, or other software (e.g. bugsigdbr), and 4. community interaction: you can request an account, contribute or analyze, learn about the project, report issues, and ask questions on the #bugsigdb channel of the community-bioc Zulip team. This collaborative effort aims to accelerate microbiome research by providing a comprehensive database of microbial signatures from published studies, along with relevant information on study design and geography, health outcomes, host body site, and experimental methods.