Fusobacterium is associated with colorectal adenomas/Experiment 1

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Reviewed Marked as Reviewed by Svetlana up on 2024-6-26

Curated date: 2024/03/14

Curator:

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Subjects

Location of subjects

United States of America

Host species Species from which microbiome was sampled. Contact us to have more species added.

Homo sapiens

Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology

Colorectal mucosa

Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology

Colorectal adenoma adenoma of large bowel,adenoma of large intestine,adenoma of the large bowel,adenoma of the large intestine,colorectal adenoma,colorectum adenoma,large bowel adenoma,large intestine adenoma,Colorectal adenoma

Group 0 name Corresponds to the control (unexposed) group for case-control studies

Non-adenoma

Group 1 name Corresponds to the case (exposed) group for case-control studies

Adenoma

Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group

Patients with colorectal adenoma

Group 0 sample size Number of subjects in the control (unexposed) group

67

Group 1 sample size Number of subjects in the case (exposed) group

48

Lab analysis

Sequencing type

16S

16S variable region One or more hypervariable region(s) of the bacterial 16S gene

V1-V3

Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance

Roche454

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).

relative abundances

Statistical test

T-Test

Significance threshold p-value or FDR threshold used for differential abundance testing (if any)

0.01

MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?

No

Signature 1

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Curated date: 2024/03/14

Curator: Uhabiba14

Revision editor(s): Uhabiba14, Scholastica, WikiWorks

Source: Figure 1

Description: Abundance of Fusobacterium in rectal mucosal biopsies from adenoma cases versus non-adenoma controls

Abundance in Group 1: increased abundance in

NCBI	Quality Control	Links
Fusobacterium

Revision editor(s): Uhabiba14, Scholastica, WikiWorks