Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates/Experiment 1
From BugSigDB
Reviewed Marked as Reviewed by Svetlana up on 2025-3-25
Subjects
- Location of subjects
- Belgium
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Abnormal stool composition Abnormal faeces composition,Abnormal feces composition,Abnormal stool composition,abnormal stool composition
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Decreasing stool consistency in Total Dataset
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Increasing stool consistency in Total Dataset
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- This group represents individuals with altered gut microbiota composition linked to fast intestinal transit in the Total Dataset.
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 months
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Spearman Correlation
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.1
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Signature 2
Reviewed Marked as Reviewed by Svetlana up on 2025-3-25
Source: Table 1
Description: Correlation between stool consistency (Bristol Stool Scale) and differentially abundant gut microbiota genera.
Abundance in Group 1: decreased abundance in Increasing stool consistency in Total Dataset
| NCBI | Quality Control | Links |
|---|---|---|
| Methanosphaera | ||
| Odoribacter | ||
| Oxalobacter | ||
| Methanobrevibacter | ||
| Akkermansia | ||
| Butyricimonas |
Revision editor(s): Francisca
