Microbial Similarity and Preference for Specific Sites in Healthy Oral Cavity and Esophagus/Experiment 4

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Reviewed Marked as Reviewed by Svetlana up on 2024-5-8

Curated date: 2024/05/04

Curator: Scholastica

Revision editor(s): WikiWorks, Scholastica, Aleru Divine, Ifeanyisam

Subjects

Location of subjects
China
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Oral cavity Bucca,Buccal cavity,Cavity of mouth,Oral cavity,oral cavity
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Health study participation health questionnaire participation,health survey participation,Health study participation,health study participation
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Supragingival plaque and Saliva
Group 1 name Corresponds to the case (exposed) group for case-control studies
Tongue dorsum
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Tongue dorsum samples of healthy individual confirmed free of periodontal diseases and no incident caries at the time of sampling by a dentist.
Group 0 sample size Number of subjects in the control (unexposed) group
27
Group 1 sample size Number of subjects in the case (exposed) group
27

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V3-V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
LEfSe
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No
LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
2


Signature 1

Reviewed Marked as Reviewed by Svetlana up on 2024-5-8

Curated date: 2024/05/04

Curator: Scholastica

Revision editor(s): Scholastica, WikiWorks

Source: Figure 5

Description: Significantly higher relative abundance in the tongue dorsum compared to other two sites

Abundance in Group 1: increased abundance in Tongue dorsum

NCBI Quality ControlLinks
Erysipelotrichia
Clostridia
SR1SR1

Revision editor(s): Scholastica, WikiWorks