Human pharyngeal microbiota in age-related macular degeneration/Experiment 3
From BugSigDB
Reviewed Marked as Reviewed by KateRasheed on 2025-7-31
Subjects
- Location of subjects
- Singapore
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Throat Gula,Throat,throat
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Microbiome Microbiome,microbiome
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Rest (The rest of the study population)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High Prevotella
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Subjects with high relative abundance of Prevotella
- Group 0 sample size Number of subjects in the control (unexposed) group
- 604
- Group 1 sample size Number of subjects in the case (exposed) group
- 27
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V6
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Linear Regression
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
- Confounders controlled for Confounding factors that have been accounted for by stratification or model adjustment
- age, sex
Signature 1
Reviewed Marked as Reviewed by KateRasheed on 2025-7-31
Source: Table 2
Description: Microbial genera significantly associated with high Prevotella relative abundance.
Abundance in Group 1: decreased abundance in High Prevotella
| NCBI | Quality Control | Links |
|---|---|---|
| Streptococcus | ||
| Porphyromonas | ||
| Granulicatella | ||
| Gemella |
Revision editor(s): Anne-mariesharp
