Gut microbiome structure and adrenocortical activity in dogs with aggressive and phobic behavioral disorders/Experiment 1
From BugSigDB
Reviewed Marked as Reviewed by ChiomaBlessing on 2025-4-29
Subjects
- Location of subjects
- Italy
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Canis lupus familiaris
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Behavior or behavioral disorder measurement Behavior or behavioral disorder measurement,behavior or behavioral disorder measurement
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Normal and Phobic behavior
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Aggressive behavior
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Dogs presenting aggressive behavior.
- Group 0 sample size Number of subjects in the control (unexposed) group
- 31
- Group 1 sample size Number of subjects in the case (exposed) group
- 11
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Random Forest Analysis
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
Signature 1
Reviewed Marked as Reviewed by ChiomaBlessing on 2025-4-29
Source: Figure 3
Description: Canine gut microbiome profile of the behavior groups aggressive (Group 1) vs. normal and phobic (Group 0).
Abundance in Group 1: increased abundance in Aggressive behavior
| NCBI | Quality Control | Links |
|---|---|---|
| Catenibacterium | ||
| Megamonas |
Revision editor(s): Asoler2004
