Skin microbiome alters attractiveness to Anopheles mosquitoes/Experiment 1
From BugSigDB
Reviewed Marked as Reviewed by Svetlana up on 2024-6-3
Subjects
- Location of subjects
- United Kingdom
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Skin of sole of pes Plantar skin of foot,Skin of plantar part of foot,Skin of sole of foot,Skin of sole of pes,skin of sole of pes
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Perceived unattractiveness to mosquitos measurement Perceived unattractiveness to mosquitos measurement,perceived unattractiveness to mosquitos measurement
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Poorly-attractive group
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Highly-attractive group
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Post-menopausal females, aged between 50 and 90 years, whose skin/body odour were highly attractive to Anopheles mosquitoes.
- Group 0 sample size Number of subjects in the control (unexposed) group
- 28
- Group 1 sample size Number of subjects in the case (exposed) group
- 27
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- raw counts
- Statistical test
- DESeq2
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Alpha Diversity
- Faith Phylogenetic diversity, takes into account phylogenetic distance of all taxa identified in a sample
- unchanged
Signature 1
Reviewed Marked as Reviewed by Svetlana up on 2024-6-3
Source: Figure 3
Description: The differential abundance of bacterial genera between attractiveness groups tested using DESEQ2
Abundance in Group 1: increased abundance in Highly-attractive group
| NCBI | Quality Control | Links |
|---|---|---|
| Methylocaldum | ||
| Sphingomonas | ||
| Staphylococcus |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Reviewed Marked as Reviewed by Svetlana up on 2024-6-3
Source: Figure 3
Description: The differential abundance of bacterial genera between attractiveness groups tested using DESEQ2
Abundance in Group 1: decreased abundance in Highly-attractive group
| NCBI | Quality Control | Links |
|---|---|---|
| Brevundimonas | ||
| Corynebacterium | ||
| Limnohabitans | ||
| Actinomycetales | ||
| Intrasporangiaceae |
Revision editor(s): Aleru Divine, WikiWorks
