Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance/Experiment 1
From BugSigDB
Reviewed Marked as Reviewed by Svetlana up on 2025-4-4
Subjects
- Location of subjects
- Israel
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Mus musculus
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Glucose tolerance test Glucose tolerance test,glucose tolerance test
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Top Responder at Day 21
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Bottom Responder at Day 21
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- The mice were recipients of the bottom sucralose responder human donors at 21 days.
- Group 0 sample size Number of subjects in the control (unexposed) group
- 3
- Group 1 sample size Number of subjects in the case (exposed) group
- 3
Lab analysis
- Sequencing type
- WMS
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- log transformation
- Statistical test
- Mixed-Effects Regression
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
- Matched on Factors on which subjects have been matched on in a case-control study
- age
Signature 1
Reviewed Marked as Reviewed by Svetlana up on 2025-4-4
Source: Table S7
Description: Linear mixed model test results of top and bottom responders bacteria at day 21 mice (Bottom vs. top day 21 bacteria).
Abundance in Group 1: increased abundance in Bottom Responder at Day 21
Revision editor(s): Shulamite
Signature 2
Reviewed Marked as Reviewed by Svetlana up on 2025-4-4
Source: Table S7
Description: Linear mixed model test results of top and bottom responders bacteria at day 21 mice (Bottom vs. top day 21 bacteria).
Abundance in Group 1: decreased abundance in Bottom Responder at Day 21
Revision editor(s): Shulamite
