Characteristics of the Gut Microbiota in Japanese Patients with Premenstrual Syndrome/Experiment 1

From BugSigDB


Needs review

Curated date: 2025/05/13

Curator: Aleru Divine

Revision editor(s): Aleru Divine

Subjects

Location of subjects
Japan
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Menstrual disorder Menstrual disorder,menstrual disorder
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Control group
Group 1 name Corresponds to the case (exposed) group for case-control studies
Premenstrual syndrome (PMS) group
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Participants who passed the criteria for premenstrual syndrome (PMS),
Group 0 sample size Number of subjects in the control (unexposed) group
144
Group 1 sample size Number of subjects in the case (exposed) group
24
Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
1 week

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V1-V3
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
centered log-ratio
Statistical test
Mann-Whitney (Wilcoxon)
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No
Confounders controlled for Confounding factors that have been accounted for by stratification or model adjustment
age

Alpha Diversity

Pielou Quantifies how equal the community is numerically
unchanged
Simpson Estimator of species richness and species evenness: more weight on species evenness
increased
Richness Number of species
increased

Signature 1

Needs review

Curated date: 2025/05/13

Curator: Aleru Divine

Revision editor(s): Aleru Divine

Source: Figure 4

Description: Significant differences in the gut microbial abundance at the genus level between the PMS and control groups.

Abundance in Group 1: increased abundance in Premenstrual syndrome (PMS) group

NCBI Quality ControlLinks
Collinsella
Blautia
Bifidobacterium
Enterocloster
Sellimonas
Thomasclavelia
Flavonifractor
Eggerthella
Phocaeicola
Dysosmobacter
Faecalimonas
Ruminococcus
Massilimicrobiota
Holdemania
Streptococcus

Revision editor(s): Aleru Divine

Signature 2

Needs review

Curated date: 2025/05/13

Curator: Aleru Divine

Revision editor(s): Aleru Divine

Source: Figure 4

Description: Significant differences in the gut microbial abundance at the genus level between the PMS and control groups.

Abundance in Group 1: decreased abundance in Premenstrual syndrome (PMS) group

NCBI Quality ControlLinks
Dialister
Oscillibacter

Revision editor(s): Aleru Divine