Specific gastrointestinal microbiota profiles in Chinese Tan sheep are associated with lauric acid content in muscle/Experiment 8
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Reviewed Marked as Reviewed by Svetlana up on 2024-7-30
Curated date: 2024/04/11
Curator: Scholastica
Revision editor(s): WikiWorks, Scholastica, Aleru Divine, Tosin
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Ovis aries
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Caecum Blind intestine,Blindgut,Caeca,Caecum,Ceca,Cecum,Intestinum caecum,Intestinum crassum caecum,Intestinum crassum cecum,caecum
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Breed animal breed,Breed,breed
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Cecum of Dorper sheep (D_C)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Cecum of Tan Sheep (T_C)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Cecum of Tan sheep bred in Ningxia, China
- Group 0 sample size Number of subjects in the control (unexposed) group
- 6
- Group 1 sample size Number of subjects in the case (exposed) group
- 6
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- LEfSe
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
- LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
- 2
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
Signature 1
Reviewed Marked as Reviewed by Svetlana up on 2024-7-30
Source: Supplementary Fig. S10
Description: LEfSe analysis of cecal microbiota in Tan sheep versus Dorper sheep from 16S data at the genus level.
Abundance in Group 1: increased abundance in Cecum of Tan Sheep (T_C)
| NCBI | Quality Control | Links |
|---|---|---|
| Pseudomonadota | ||
| uncultured Oscillospiraceae bacterium |
Revision editor(s): Scholastica, WikiWorks
Signature 2
Reviewed Marked as Reviewed by Svetlana up on 2024-7-30
Source: Supplementary Fig. S10
Description: LEfSe analysis of cecal microbiota in Tan sheep versus Dorper sheep from 16S data at the genus level.
Abundance in Group 1: decreased abundance in Cecum of Tan Sheep (T_C)
| NCBI | Quality Control | Links |
|---|---|---|
| Actinomycetota |
Revision editor(s): Scholastica, WikiWorks
