Gut microbiota affects the estrus return of sows by regulating the metabolism of sex steroid hormones/Experiment 3

From BugSigDB


Reviewed Marked as Reviewed by KateRasheed on 2025-6-11

Curated date: 2025/05/11

Curator: Victoria

Revision editor(s): Victoria

Subjects

Location of subjects
China
Host species Species from which microbiome was sampled. Contact us to have more species added.
Sus scrofa domesticus
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Sex hormone Geschlechtshormon,Geschlechtshormone,hormone sexuelle,hormones sexuelles,sex hormones,Sexualhormon,Sexualhormone,Sex hormone,sex hormone
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Non-return Sows (Validation cohort)
Group 1 name Corresponds to the case (exposed) group for case-control studies
Normal Return Sows (Validation cohort)
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
This group comprises sows that returned to estrus within 7 days of weaning in the validation cohort.
Group 0 sample size Number of subjects in the control (unexposed) group
11
Group 1 sample size Number of subjects in the case (exposed) group
18

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
LEfSe
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.1
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No
LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
2

Alpha Diversity

Shannon Estimator of species richness and species evenness: more weight on species richness
unchanged
Chao1 Abundance-based estimator of species richness
unchanged
Richness Number of species
unchanged

Signature 1

Reviewed Marked as Reviewed by KateRasheed on 2025-6-11

Curated date: 2025/05/11

Curator: Victoria

Revision editor(s): Victoria

Source: Additional file1: Figure S6D

Description: Differential bacterial species between normal return and non-return sows with metagenomic sequencing data in the validation cohort.

Abundance in Group 1: increased abundance in Normal Return Sows (Validation cohort)

NCBI Quality ControlLinks
Lactobacillus johnsonii
Rikenellaceae bacterium
Lactobacillus delbrueckii
Lactobacillus crispatus
Verrucomicrobiota bacterium
Lactobacillus gasseri
Porphyromonadaceae bacterium
Lactobacillus helveticus
Limosilactobacillus fermentum
Lactobacillus taiwanensis
Jonquetella anthropi

Revision editor(s): Victoria

Signature 2

Reviewed Marked as Reviewed by KateRasheed on 2025-6-11

Curated date: 2025/05/11

Curator: Victoria

Revision editor(s): Victoria

Source: Additional file1: Figure S6D

Description: Differential bacterial species between normal return and non-return sows with metagenomic sequencing data in the validation cohort.

Abundance in Group 1: decreased abundance in Normal Return Sows (Validation cohort)

NCBI Quality ControlLinks
[Eubacterium] siraeum
Bifidobacterium pseudolongum
Streptococcus suis
[Ruminococcus] lactaris
Streptococcus equinus
Collinsella aerofaciens
bacterium D16-59
Criibacterium bergeronii
Psychrobacter piechaudii
Bacteroidales bacterium
Bacteroides faecis
Clostridium tertium
Anaerobutyricum hallii
Aerococcus viridans
Streptococcus constellatus
Synergistes jonesii

Revision editor(s): Victoria