Taxonomic intestinal microbiota differences in Lewy body spectrum disease and cohabitant controls/Experiment 3
From BugSigDB
Needs review
Subjects
- Location of subjects
- United States of America
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- REM sleep behavior disorder Rapid eye movement sleep behavior disorder,rapid eye movement sleep behavior disorder,REM Sleep Behavior Disorder,REM sleep behavior disorder,rEM sleep behavior disorder
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Healthy cohort
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- iRBD cases
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- isolated REM sleep behavior disorder (iRBD) cases
- Group 0 sample size Number of subjects in the control (unexposed) group
- 19
- Group 1 sample size Number of subjects in the case (exposed) group
- 11
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Kruskall-Wallis
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.0083
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Signature 1
Needs review
Source: Figure 1
Description: Taxa enriched in iRBD cases
Abundance in Group 1: increased abundance in iRBD cases
| NCBI | Quality Control | Links |
|---|---|---|
| Blautia |
Revision editor(s): Kristin.abraham
Signature 2
Needs review
Source: Figure 1
Description: Taxa depleted in iRBD cases
Abundance in Group 1: decreased abundance in iRBD cases
| NCBI | Quality Control | Links |
|---|---|---|
| Alistipes | ||
| Bacteroides |
Revision editor(s): Kristin.abraham
