Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn's disease
-
Quality control
- Retracted paper
- Contamination issues suspected
- Batch effect issues suspected
- Uncontrolled confounding suspected
- Results are suspect (various reasons)
- Tags applied
Experiment 1
Subjects
- Location of subjects
- Germany
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Mus musculus
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Response to transplant Response to transplant,response to transplant
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Model Patient 1 (MP1) with inactive disease
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Model Patient 1 (MP1) with active disease
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Gnotobiotic Il10−/− mice subjected to fecal microbiota transplantation (FMT) from Model Patient 1 (MP1), resulting in recipients exhibiting inflammation
Lab analysis
- Sequencing type
- WMS
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- LEfSe
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
- LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
- 2.0
Signature 1
Source: Figure 5D
Description: LEfSe (Linear discriminant analysis Effect Size) analysis of differentially abundant bacteria at species level in all recipient inflamed (active, red) or non-inflamed (inactive, green) Il10-/- mice from all FMTs performed with abundance of strains in model patient 1 (MP1).
Abundance in Group 1: increased abundance in Model Patient 1 (MP1) with active disease
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure 5D
Description: LEfSe (Linear discriminant analysis Effect Size) analysis of differentially abundant bacteria at species level in all recipient inflamed (active, red) or non-inflamed (inactive, green) Il10-/- mice from all FMTs performed with abundance of strains in model patient 1 (MP1).
Abundance in Group 1: decreased abundance in Model Patient 1 (MP1) with active disease
Revision editor(s): Aleru Divine, WikiWorks
Experiment 2
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Model Patient 2 (MP2) with inactive disease
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Model Patient 2 (MP2) with active disease
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Gnotobiotic Il10−/− mice subjected to fecal microbiota transplantation (FMT) from Model Patient 2 (MP2), resulting in recipients exhibiting inflammation
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 5E
Description: LEfSe (Linear discriminant analysis Effect Size) analysis of differentially abundant bacteria at species level in all recipient inflamed (active, red) or non-inflamed (inactive, green) Il10-/- mice from all FMTs performed with abundance of strains in model patient 2 (MP2).
Abundance in Group 1: increased abundance in Model Patient 2 (MP2) with active disease
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure 5E
Description: LEfSe (Linear discriminant analysis Effect Size) analysis of differentially abundant bacteria at species level in all recipient inflamed (active, red) or non-inflamed (inactive, green) Il10-/- mice from all FMTs performed with abundance of strains in model patient 2 (MP2).
Abundance in Group 1: decreased abundance in Model Patient 2 (MP2) with active disease
| NCBI | Quality Control | Links |
|---|---|---|
| Bacteroides uniformis | ||
| Eggerthella lenta | ||
| Enterocloster bolteae | ||
| Enterocloster clostridioformis | ||
| Flavonifractor plautii | ||
| Thomasclavelia spiroformis | ||
| [Clostridium] scindens |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 3
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Model Patient 3 (MP3) with inactive disease
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Model Patient 3 (MP3) with active disease
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Gnotobiotic Il10−/− mice subjected to fecal microbiota transplantation (FMT) from Model Patient 3 (MP3), resulting in recipients exhibiting inflammation
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 5F
Description: LEfSe (Linear discriminant analysis Effect Size) analysis of differentially abundant bacteria at species level in all recipient inflamed (active, red) or non-inflamed (inactive, green) Il10-/- mice from all FMTs performed with abundance of strains in model patient 3 (MP3).
Abundance in Group 1: increased abundance in Model Patient 3 (MP3) with active disease
| NCBI | Quality Control | Links |
|---|---|---|
| Enterocloster clostridioformis | ||
| Eggerthella lenta | ||
| Flavonifractor plautii | ||
| Enterocloster bolteae | ||
| Ruthenibacterium lactatiformans | ||
| Mediterraneibacter gnavus |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure 5F
Description: LEfSe (Linear discriminant analysis Effect Size) analysis of differentially abundant bacteria at species level in all recipient inflamed (active, red) or non-inflamed (inactive, green) Il10-/- mice from all FMTs performed with abundance of strains in model patient 3 (MP3).
Abundance in Group 1: decreased abundance in Model Patient 3 (MP3) with active disease
| NCBI | Quality Control | Links |
|---|---|---|
| Clostridium perfringens | ||
| Enterococcus faecalis | ||
| Niameybacter | ||
| Thomasclavelia ramosa | ||
| [Clostridium] innocuum |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 4
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Inactive group
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Active group
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Gnotobiotic Il10−/− mice subjected to fecal microbiota transplantation (FMT) from MP1 - MP3, resulting in recipients exhibiting inflammation
Lab analysis
Statistical Analysis
Alpha Diversity
- Richness Number of species
- decreased
Signature 1
Source: Figure S9A
Description: LEfSe (Linear discriminant analysis Effect Size) analysis of differentially abundant bacteria at species level in all recipient inflamed (active, red) or non-inflamed (inactive, green) Il10-/- mice from all FMTs performed with abundance of strains in each model patient (MP).
Abundance in Group 1: increased abundance in Active group
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure S9A
Description: LEfSe (Linear discriminant analysis Effect Size) analysis of differentially abundant bacteria at species level in all recipient inflamed (active, red) or non-inflamed (inactive, green) Il10-/- mice from all FMTs performed with abundance of strains in each model patient (MP).
Abundance in Group 1: decreased abundance in Active group
Revision editor(s): Aleru Divine, WikiWorks
Experiment 5
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Response to diet Response to diet,response to diet
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Chow diet
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Exclusive enteral nutrition (EEN)-like diet
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Mice fed with exclusive enteral nutrition (EEN)-like diet for 4 weeks after getting Fecal microbiota from MP3 (Model Patient 3)
Lab analysis
Statistical Analysis
Signature 1
Source: Figure S9B
Description: LEfSe analysis of differentially abundant bacteria at species level based on metagenomic data in mouse experiments from MP1- MP3 (including relapse) based on mouse diet.
Abundance in Group 1: increased abundance in Exclusive enteral nutrition (EEN)-like diet
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure S9B
Description: LEfSe analysis of differentially abundant bacteria at species level based on metagenomic data in mouse experiments from MP1- MP3 (including relapse) based on mouse diet.
Abundance in Group 1: decreased abundance in Exclusive enteral nutrition (EEN)-like diet
Revision editor(s): Aleru Divine, WikiWorks
Experiment 6
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Exposure Exposure,exposure
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Unsorted cells
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Ethanol (EtOH)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 1 (MP1) samples dissolved in ethanol.
Lab analysis
Statistical Analysis
- Statistical test
- ANOVA
- LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
- Not specified
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched zOTUs in MP1.
Abundance in Group 1: increased abundance in Ethanol (EtOH)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 7
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Lauric Acid (LA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 1 (MP1) samples after exposure to Lauric Acid (LA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched zOTUs in MP1.
Abundance in Group 1: increased abundance in Lauric Acid (LA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 8
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Decanoic Acid (DA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 1 (MP1) samples after exposure to Decanoic Acid (DA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched zOTUs in MP1.
Abundance in Group 1: increased abundance in Decanoic Acid (DA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 9
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Octanoic Acid (OA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 1 (MP1) samples after exposure to Octanoic Acid (OA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched zOTUs in MP1
Abundance in Group 1: increased abundance in Octanoic Acid (OA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 10
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Ethanol (EtOH)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Lauric Acid (LA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 1 (MP1) samples after exposure to Lauric Acid (LA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched zOTUs in MP1
Abundance in Group 1: increased abundance in Lauric Acid (LA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 11
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Decanoic Acid (DA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 1 (MP1) samples after exposure to Decanoic Acid (DA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched zOTUs in MP1.
Abundance in Group 1: increased abundance in Decanoic Acid (DA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 12
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Octanoic Acid (OA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 1 (MP1) samples after exposure to Octanoic Acid (OA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched zOTUs in MP1
Abundance in Group 1: increased abundance in Octanoic Acid (OA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli | ||
| Lachnospiraceae |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 13
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Unsorted cells
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Ethanol (EtOH)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 3 (MP3) samples dissolved in ethanol.
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched zOTUs in MP3.
Abundance in Group 1: increased abundance in Ethanol (EtOH)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 14
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Lauric Acid (LA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 3 (MP3) samples after exposure to Lauric Acid (LA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched zOTUs in MP3.
Abundance in Group 1: increased abundance in Lauric Acid (LA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 15
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Decanoic Acid (DA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 3 (MP3) samples after exposure to Decanoic Acid (DA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched zOTUs in MP3.
Abundance in Group 1: increased abundance in Decanoic Acid (DA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 16
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Octanoic Acid (OA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 3 (MP3) samples after exposure to Octanoic Acid (OA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched zOTUs in MP3.
Abundance in Group 1: increased abundance in Octanoic Acid (OA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 17
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Ethanol (EtOH)
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched zOTUs in MP3.
Abundance in Group 1: increased abundance in Octanoic Acid (OA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 18
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Unsorted cells
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Ethanol (EtOH)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) samples dissolved in ethanol.
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: increased abundance in Ethanol (EtOH)
| NCBI | Quality Control | Links |
|---|---|---|
| Peptostreptococcus anaerobius |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: decreased abundance in Ethanol (EtOH)
| NCBI | Quality Control | Links |
|---|---|---|
| [Clostridium] scindens | ||
| Thomasclavelia ramosa | ||
| Ruthenibacterium lactatiformans | ||
| Phocaeicola vulgatus |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 19
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Lauric Acid (LA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) samples after exposure to Lauric Acid (LA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: increased abundance in Lauric Acid (LA)
| NCBI | Quality Control | Links |
|---|---|---|
| Enterocloster bolteae | ||
| Enterocloster aldenensis | ||
| Eggerthella lenta |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: decreased abundance in Lauric Acid (LA)
| NCBI | Quality Control | Links |
|---|---|---|
| Hungatella hominis | ||
| Phocaeicola vulgatus | ||
| Ruthenibacterium lactatiformans | ||
| Thomasclavelia ramosa | ||
| [Clostridium] scindens |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 20
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Decanoic Acid (DA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) samples after exposure to Decanoic Acid (DA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: increased abundance in Decanoic Acid (DA)
| NCBI | Quality Control | Links |
|---|---|---|
| Enterocloster bolteae | ||
| Enterocloster aldenensis |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: decreased abundance in Decanoic Acid (DA)
| NCBI | Quality Control | Links |
|---|---|---|
| Hungatella hominis | ||
| Phocaeicola vulgatus | ||
| Ruthenibacterium lactatiformans | ||
| Thomasclavelia ramosa | ||
| [Clostridium] scindens | ||
| Peptostreptococcus anaerobius |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 21
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Octanoic Acid (OA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) samples after exposure to Octanoic Acid (OA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: increased abundance in Octanoic Acid (OA)
| NCBI | Quality Control | Links |
|---|---|---|
| Enterocloster aldenensis | ||
| Enterocloster bolteae |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: decreased abundance in Octanoic Acid (OA)
| NCBI | Quality Control | Links |
|---|---|---|
| Hungatella hominis | ||
| Phocaeicola vulgatus | ||
| Ruthenibacterium lactatiformans | ||
| Thomasclavelia ramosa | ||
| [Clostridium] scindens |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 22
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Ethanol (EtOH)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Lauric Acid (LA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) samples after exposure to Lauric Acid (LA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: increased abundance in Lauric Acid (LA)
| NCBI | Quality Control | Links |
|---|---|---|
| Enterocloster bolteae | ||
| Enterocloster aldenensis | ||
| Eggerthella lenta |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: decreased abundance in Lauric Acid (LA)
| NCBI | Quality Control | Links |
|---|---|---|
| Peptostreptococcus anaerobius |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 23
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Decanoic Acid (DA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) samples after exposure to Decanoic Acid (DA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: increased abundance in Decanoic Acid (DA)
| NCBI | Quality Control | Links |
|---|---|---|
| Enterocloster bolteae | ||
| Enterocloster aldenensis |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: decreased abundance in Decanoic Acid (DA)
| NCBI | Quality Control | Links |
|---|---|---|
| Peptostreptococcus anaerobius | ||
| [Clostridium] scindens |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 24
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Octanoic Acid (OA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) samples after exposure to Octanoic Acid (OA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: increased abundance in Octanoic Acid (OA)
| NCBI | Quality Control | Links |
|---|---|---|
| Enterocloster bolteae | ||
| Enterocloster aldenensis |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure 2E
Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.
Abundance in Group 1: decreased abundance in Octanoic Acid (OA)
| NCBI | Quality Control | Links |
|---|---|---|
| Hungatella hominis | ||
| Peptostreptococcus anaerobius | ||
| Ruthenibacterium lactatiformans | ||
| Thomasclavelia ramosa |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 25
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Unsorted cells
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Lauric Acid (LA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) relapse samples after exposure to Lauric Acid (LA).
- Group 1 sample size Number of subjects in the case (exposed) group
- 19
Lab analysis
Statistical Analysis
Signature 1
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse
Abundance in Group 1: increased abundance in Lauric Acid (LA)
| NCBI | Quality Control | Links |
|---|---|---|
| Dialister invisus | ||
| Escherichia coli | ||
| Eubacterium | ||
| [Clostridium] scindens | ||
| Sporobacter PAC001306Sporobacter PAC001306 | ||
| Sporobacter PAC001556Sporobacter PAC001556 |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse
Abundance in Group 1: decreased abundance in Lauric Acid (LA)
| NCBI | Quality Control | Links |
|---|---|---|
| Hominenteromicrobium mulieris |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 26
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Decanoic Acid (DA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) relapse samples after exposure to Decanoic Acid (DA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse.
Abundance in Group 1: increased abundance in Decanoic Acid (DA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli | ||
| Sorobacter PAC001556Sorobacter PAC001556 |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse.
Abundance in Group 1: decreased abundance in Decanoic Acid (DA)
| NCBI | Quality Control | Links |
|---|---|---|
| Anaerostipes hadrus | ||
| Hominenteromicrobium mulieris |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 27
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Octanoic Acid (OA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) relapse samples after exposure to Octanoic Acid (OA).
- Group 1 sample size Number of subjects in the case (exposed) group
- 20
Lab analysis
Statistical Analysis
Signature 1
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse.
Abundance in Group 1: increased abundance in Octanoic Acid (OA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli | ||
| Dialister invisus | ||
| Sporobacter PAC001556Sporobacter PAC001556 |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse.
Abundance in Group 1: decreased abundance in Octanoic Acid (OA)
| NCBI | Quality Control | Links |
|---|---|---|
| Anaerostipes hadrus | ||
| Hominenteromicrobium mulieris |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 28
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Ethanol (EtOH)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Lauric Acid (LA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) samples after exposure to Lauric Acid (LA).
- Group 0 sample size Number of subjects in the control (unexposed) group
- 20
- Group 1 sample size Number of subjects in the case (exposed) group
- 19
Lab analysis
Statistical Analysis
Signature 1
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse.
Abundance in Group 1: increased abundance in Lauric Acid (LA)
| NCBI | Quality Control | Links |
|---|---|---|
| Eubacterium | ||
| [Clostridium] scindens | ||
| Sporobacter PAC001556Sporobacter PAC001556 |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 29
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Decanoic Acid (DA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) samples after exposure to Decanoic Acid (DA).
Lab analysis
Statistical Analysis
Signature 1
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse.
Abundance in Group 1: increased abundance in Decanoic Acid (DA)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse.
Abundance in Group 1: decreased abundance in Decanoic Acid (DA)
| NCBI | Quality Control | Links |
|---|---|---|
| Anaerostipes hadrus | ||
| Hominenteromicrobium mulieris |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 30
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Octanoic Acid (OA)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) relapse samples after exposure to Octanoic Acid (OA).
- Group 1 sample size Number of subjects in the case (exposed) group
- 20
Lab analysis
Statistical Analysis
Signature 1
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse.
Abundance in Group 1: increased abundance in Octanoic Acid (OA)
| NCBI | Quality Control | Links |
|---|---|---|
| Dialister invisus |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse.
Abundance in Group 1: decreased abundance in Octanoic Acid (OA)
| NCBI | Quality Control | Links |
|---|---|---|
| Hominenteromicrobium mulieris |
Revision editor(s): Aleru Divine, WikiWorks
Experiment 31
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Unsorted cells
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Ethanol (EtOH)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Model Patient 2 (MP2) relapse samples dissolved in ethanol.
- Group 0 sample size Number of subjects in the control (unexposed) group
- Not specified
Lab analysis
Statistical Analysis
Signature 1
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse.
Abundance in Group 1: increased abundance in Ethanol (EtOH)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli | ||
| Sporobacter PAC001306Sporobacter PAC001306 | ||
| Sporobacter PAC001556Sporobacter PAC001556 |
Revision editor(s): Aleru Divine, WikiWorks
Signature 2
Source: Figure S4
Description: Relative abundances of significant enriched and depleted zOTUs in MP2 relapse.
Abundance in Group 1: decreased abundance in Ethanol (EtOH)
| NCBI | Quality Control | Links |
|---|---|---|
| Hominenteromicrobium mulieris |
Revision editor(s): Aleru Divine, WikiWorks
Contents
- 1 Experiment 1
- 2 Experiment 2
- 3 Experiment 3
- 4 Experiment 4
- 5 Experiment 5
- 6 Experiment 6
- 7 Experiment 7
- 8 Experiment 8
- 9 Experiment 9
- 10 Experiment 10
- 11 Experiment 11
- 12 Experiment 12
- 13 Experiment 13
- 14 Experiment 14
- 15 Experiment 15
- 16 Experiment 16
- 17 Experiment 17
- 18 Experiment 18
- 19 Experiment 19
- 20 Experiment 20
- 21 Experiment 21
- 22 Experiment 22
- 23 Experiment 23
- 24 Experiment 24
- 25 Experiment 25
- 26 Experiment 26
- 27 Experiment 27
- 28 Experiment 28
- 29 Experiment 29
- 30 Experiment 30
- 31 Experiment 31
