New insights into the combined effects of aflatoxin B1 and Eimeria ovinoidalis on uterine function by disrupting the gut-blood-reproductive axis in sheep/Experiment 7
From BugSigDB
Reviewed Marked as Reviewed by Svetlana up on 2025-3-28
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Ovis aries
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Coccidiosis Coccidiosis,coccidiosis,Coccidiosis (& [intestinal]),coccidiosis (& [intestinal]),intestinal coccidiosis
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Con (Control) treatment group
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- AFB1 (Aflatoxin B1) treatment group
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Treatment group with Aflatoxin B1 which is a mycotoxin produced by Aspergillus flavus and Aspergillus parasiticus, is a member of the aflatoxin family and is commonly found in cereals and animal feed all over the world, together with other fungal toxins and received daily oral administration of AFB1 at a dosage of 60 μg/kg
- Group 0 sample size Number of subjects in the control (unexposed) group
- 4
- Group 1 sample size Number of subjects in the case (exposed) group
- 4
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Dunn's test
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Chao1 Abundance-based estimator of species richness
- unchanged
- Simpson Estimator of species richness and species evenness: more weight on species evenness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Reviewed Marked as Reviewed by Svetlana up on 2025-3-28
Source: Figure 3I
Description: Relative abundance analysis of common differential genera
Abundance in Group 1: decreased abundance in AFB1 (Aflatoxin B1) treatment group
| NCBI | Quality Control | Links |
|---|---|---|
| Eubacterium |
Revision editor(s): Tosin
