Comparative study of gut microbiota reveals the adaptive strategies of gibbons living in suboptimal habitats/Experiment 2

From BugSigDB


Needs review

Curated date: 2025/03/03

Curator: KateRasheed

Revision editor(s): KateRasheed

Subjects

Location of subjects
China
Host species Species from which microbiome was sampled. Contact us to have more species added.
Nomascus concolor
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Diet measurement Diet measurement,diet measurement
Group 0 name Corresponds to the control (unexposed) group for case-control studies
High + Middle feeding group - Nomascus concolor
Group 1 name Corresponds to the case (exposed) group for case-control studies
Low feeding group - Nomascus concolor
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
These refers to gibbon species living in suboptimal habitats with lower and more variable fruit availability, relying more on leaves. They consumed low proportion of leaf per month.

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
LEfSe
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes
LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
2


Signature 1

Needs review

Curated date: 2025/03/03

Curator: KateRasheed

Revision editor(s): KateRasheed

Source: Fig. 5, Supplementary Table 6

Description: Linear Discriminant Analysis Effect Size (LEfSe) analyses revealed significant contributions to the differences in abundance across various bacteria taxonomic levels, from phylum to genus, among different gibbon species with varying proportions of leaf consumption.

Abundance in Group 1: increased abundance in Low feeding group - Nomascus concolor

NCBI Quality ControlLinks
Acholeplasmataceae
Acholeplasmatales
Anaeroplasma
Bacilli
Bacillota
uncultured bacterium
Prevotellaceae NK3B31_groupPrevotellaceae NK3B31_group
Bacteroides
unclassified Bacteroides
Bacteroidaceae
Prevotellaceae UCG-001Prevotellaceae UCG-001
Marseilla massiliensis

Revision editor(s): KateRasheed