Comparative study of gut microbiota reveals the adaptive strategies of gibbons living in suboptimal habitats/Experiment 5

From BugSigDB


Needs review

Curated date: 2025/03/03

Curator: KateRasheed

Revision editor(s): KateRasheed

Subjects

Location of subjects
China
Host species Species from which microbiome was sampled. Contact us to have more species added.
Hoolock tianxing
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Diet measurement Diet measurement,diet measurement
Group 0 name Corresponds to the control (unexposed) group for case-control studies
High + Middle feeding group - Hoolock tianxing
Group 1 name Corresponds to the case (exposed) group for case-control studies
Low feeding group - Hoolock tianxing
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
These refers to gibbon species living in suboptimal habitats with lower and more variable fruit availability, relying more on leaves. They had the lowest monthly fruit intake. This group consumed low proportion of leaf per month.

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
LEfSe
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No
LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
2


Signature 1

Needs review

Curated date: 2025/03/03

Curator: KateRasheed

Revision editor(s): KateRasheed

Source: Fig. 5, Supplementary Table 6

Description: Linear Discriminant Analysis Effect Size (LEfSe) analyses revealed significant contributions to the differences in abundance across various bacteria taxonomic levels, from phylum to genus, among different gibbon species with varying proportions of leaf consumption.

Abundance in Group 1: increased abundance in Low feeding group - Hoolock tianxing

NCBI Quality ControlLinks
Acholeplasma
Acholeplasmataceae
Acholeplasmatales
Alloprevotella
Atopobiaceae
Atopobium
Bacilli
Bacteroidaceae
Bacteroides
Candidatus Gastranaerophilales
Clostridiaceae
Coprococcus
Coprococcus eutactus
Cyanobacteriota
Eubacteriales
Sarcina
Vampirovibrio
unclassified Bacteroides
unclassified Clostridia
unclassified Sutterella
uncultured Bacteroidales bacterium
uncultured bacterium
uncultured rumen bacterium
Vampirovibriophyceae
Lachnospiraceae NK3A20_groupLachnospiraceae NK3A20_group
Erysipelatoclostridiaceae UCG-004Erysipelatoclostridiaceae UCG-004
Clostridia UCG-014Clostridia UCG-014
Prevotellaceae UCG-001Prevotellaceae UCG-001
unclassified Sarcina

Revision editor(s): KateRasheed