Gut microbiome changes with micronutrient supplementation in children with attention-deficit/hyperactivity disorder: the MADDY study/Experiment 8

From BugSigDB


Reviewed Marked as Reviewed by Svetlana up on 2025-4-14

Curated date: 2025/04/09

Curator: Mautin

Revision editor(s): Mautin

Subjects

Location of subjects
Canada
United States of America
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Micronutrient Micronutrient,micronutrient
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Micronutrients Only before micronutrients
Group 1 name Corresponds to the case (exposed) group for case-control studies
Micronutrients Only after micronutrients
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
These are participants who received only micronutrients from baseline to week 8 .
Group 0 sample size Number of subjects in the control (unexposed) group
33
Group 1 sample size Number of subjects in the case (exposed) group
33

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Mann-Whitney (Wilcoxon)
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No


Signature 1

Reviewed Marked as Reviewed by Svetlana up on 2025-4-14

Curated date: 2025/04/09

Curator: Mautin

Revision editor(s): Mautin

Source: Table S6

Description: Significant Bacterial Taxa Abundance Within Group Change Following Micronutrients Only.

Abundance in Group 1: increased abundance in Micronutrients Only after micronutrients

NCBI Quality ControlLinks
Bacteroides
Bacteroidaceae
Rikenellaceae
Bacteroidota

Revision editor(s): Mautin

Signature 2

Reviewed Marked as Reviewed by Svetlana up on 2025-4-14

Curated date: 2025/04/09

Curator: Mautin

Revision editor(s): Mautin

Source: Table S6

Description: Significant Bacterial Taxa Abundance Within Group Change Following Micronutrients Only.

Abundance in Group 1: decreased abundance in Micronutrients Only after micronutrients

NCBI Quality ControlLinks
Agathobacter
Bifidobacteriaceae
Bifidobacterium
Blautia
Lachnospiraceae
Subdoligranulum
Actinomycetota

Revision editor(s): Mautin