Rhodococcus spp. interacts with human norovirus in clinical samples and impairs its replication on human intestinal enteroids/Experiment 3
From BugSigDB
Reviewed Marked as Reviewed by Svetlana up on 2025-4-14
Subjects
- Location of subjects
- Spain
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Viral disease infection, viral,infections, Viruses,viral disease,viral disorder,viral infection,viral infectious disease,virus infection,Viruses caused disease or disorder,Viruses disease or disorder,Viruses infection,Viruses infectious disease,Viral disease
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Anti-NoV GII.4 Sydney 2012 antibody. (NoV)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Isotype control antibody (N)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Bacteria not recognized by the isotype control antibody nor the specific antibody
- Group 0 sample size Number of subjects in the control (unexposed) group
- 1
- Group 1 sample size Number of subjects in the case (exposed) group
- 1
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Dunn's test
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
Signature 1
Reviewed Marked as Reviewed by Svetlana up on 2025-4-14
Source: Fig 1b and S2b
Description: Normalized counts of reads corresponding to Lactobacillus taiwanensis/johnsonii and Ligilactobacillus murinus/animalis and Abundance of Rhodococcus taxons. p<0.05 for Sidak's test comparing NoV subgroup with the rest of subgroups.
Abundance in Group 1: decreased abundance in Isotype control antibody (N)
| NCBI | Quality Control | Links |
|---|---|---|
| Rhodococcus | ||
| Ligilactobacillus murinus/animalisLigilactobacillus murinus/animalis |
