Maternal balanced energy-protein supplementation reshapes the maternal gut microbiome and enhances carbohydrate metabolism in infants: a randomized controlled trial/Experiment 1
From BugSigDB
Subjects
- Location of subjects
- Burkina Faso
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Balanced reciprocal translocation Balanced reciprocal translocation,balanced reciprocal translocation
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Mother / Infant Control
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Mother / Infant Intervention
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- This group consists of taxa shared between mothers and infants across time points from third trimester, 1-2 months and 5–6 months postpartum.
- Group 0 sample size Number of subjects in the control (unexposed) group
- 131
- Group 1 sample size Number of subjects in the case (exposed) group
- 122
Lab analysis
- Sequencing type
- WMS
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- log transformation
- Statistical test
- ANCOM-BC2
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- increased
- Simpson Estimator of species richness and species evenness: more weight on species evenness
- increased
- Richness Number of species
- increased
Signature 1
Source: Fig. 3C
Description: Relative abundance of taxa shared between mothers and infants across time points
Abundance in Group 1: increased abundance in Mother / Infant Intervention
| NCBI | Quality Control | Links |
|---|---|---|
| Bacteroides fragilis | ||
| Escherichia coli | ||
| Bacteroides fragilis ABacteroides fragilis A | ||
| Prevotella sp.900544825Prevotella sp.900544825 |
Revision editor(s): Joiejoie
Signature 2
Source: Fig. 3C
Description: Relative abundance of taxa shared between mothers and infants across time points
Abundance in Group 1: decreased abundance in Mother / Infant Intervention
| NCBI | Quality Control | Links |
|---|---|---|
| Veillonella sp. | ||
| Veillonella parvula |
Revision editor(s): Joiejoie
