ANE syndrome

From BugSigDB

ANE syndrome is a rare, genetic, neuro-endocrino-cutaneous disorder characterized by highly variable degrees of alopecia, moderate to severe intellectual disability, progressive, late-onset motor deterioration and combined anterior pituitary hormone deficiency, manifesting with central hypogonadotropic hypogonadism, delayed or absent puberty, growth hormone deficiency (resulting in short stature), progressive central adrenal insufficiency and a hypoplastic anterior pituitary gland. Additional features include hypodontia, flexural reticulate hyperpigmentation, gynecomastia, microcephaly and kyphoscoliosis.
  • Alopecia - progressive neurological defect - endocrinopathy
  • alopecia, neurologic defects, and endocrinopathy syndrome
  • alopecia-progressive neurological defect-endocrinopathy syndrome
  • ANE syndrome
  • ANE syndrome
  • anes