Acute hepatic porphyria
From BugSigDB
A group of metabolic diseases due to deficiency of one of a number of liver enzymes in the biosynthetic pathway of heme. They are characterized by the accumulation and increased excretion of porphyrins or its precursors. Clinical features include neurological symptoms (porphyria, acute intermittent), cutaneous lesions due to photosensitivity (porphyria cutanea tarda), or both (hereditary coproporphyria). Hepatic porphyrias can be hereditary or acquired as a result of toxicity to the hepatic tissues.
- Aliases
- acute hepatic porphyria
- acute porphyria
- ALAD deficiency
- Delta-aminolevulinate dehydratase deficiency
- hepatic porphyria
- hepatic porphyria
- hepatic Porphyrias
- liver porphyria
- porphobilinogen synthase deficiency
- porphyria of liver
- porphyria, hepatic
