Acute promyelocytic leukemia

From BugSigDB


Acute promyelocytic leukemia (APL) is an aggressive form of acute myeloid leukemia (AML), characterized by arrest of leukocyte differentiation at the promyelocyte stage, due to a specific chromosomal translocation t(15;17) in myeloid cells. APL manifests with easy bruising, hemorrhagic diathesis and fatigue.
Aliases
  • acute myeloblastic leukemia 3
  • acute myeloblastic leukemia type 3
  • acute myeloid leukemia M3
  • acute myeloid leukemia with t(15;17)(q22;q12);(PML/RARalpha) and variants
  • acute promyelocytic leukemia
  • acute promyelocytic leukemia
  • acute promyelocytic leukemia
  • acute promyelocytic leukemia with PML-rara
  • acute promyelocytic leukemia with t(15;17)(q22;q12); PML-rara
  • acute promyelocytic leukemia with t(15;17)(q22;q12); PML/rara
  • AML M3
  • AML with t(15;17)(q22;q12)
  • AML with t(15;17)(q22;q12);(PML/RARalpha) and variants
  • APL
  • APML
  • APML - acute promyelocytic leukemia
  • FAB M3
  • leukemia, acute promyelocytic
  • promyelocytic leukemia