Amyotrophic lateral sclerosis

A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts (MeSH).

Aliases

ALS
ALS (Amyotrophic Lateral Sclerosis)
ALS - Amyotrophic lateral sclerosis
amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (disorder)
Amyotrophic Lateral Sclerosis With Dementia
Amyotrophic Lateral Sclerosis, Guam Form
Amyotrophic lateral sclerosis, Parkinsonism/Dementia complex of Guam
Amyotrophic Lateral Sclerosis-Parkinsonism/dementia Complex 1
AMYOTROPHIC SCLEROSIS
Bulbar motor neuron disease
Charcot disease
Dementia With Amyotrophic Lateral Sclerosis
Disease, Lou-Gehrigs
Gehrig Disease
Gehrig's Disease
GEHRIGS DIS
Gehrigs Disease
Guam Form of Amyotrophic Lateral Sclerosis
Lateral Scleroses, Amyotrophic
LOU GEHRIG DIS
Lou Gehrig Disease
Lou Gehrig disease
Lou Gehrig's Disease
Lou Gehrig's disease
LOU GEHRIGS DIS
Lou Gehrigs Disease
Lou-Gehrigs Disease
MOTOR NEURON DIS AMYOTROPHIC LATERAL SCLEROSIS
Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Motor neuron disease, bulbar
motor neuron disease, bulbar
Sclerosis, Amyotrophic Lateral

Studies related to Amyotrophic lateral sclerosis Advanced search

The alteration of gut microbiome and metabolism in amyotrophic lateral sclerosis patients