Data transformation definitions

Examples of metagenomic data transformation methods

Lloréns-Rico, V., Vieira-Silva, S., Gonçalves, P.J. et al. Benchmarking microbiome transformations favors experimental quantitative approaches to address compositionality and sampling depth biases. Nat Commun 12, 3562 (2021). https://doi.org/10.1038/s41467-021-23821-6

Method	Transformation
Raw sequencing data	Relative
Relative abundance	Relative
Relative microbiome profiling	Relative
Arcsine square root	Relative
Centered log ratio	Compositional
Absolute count scaling	Quantitative