Data transformation definitions

From BugSigDB

Examples of metagenomic data transformation methods[edit]

Lloréns-Rico, V., Vieira-Silva, S., Gonçalves, P.J. et al. Benchmarking microbiome transformations favors experimental quantitative approaches to address compositionality and sampling depth biases. Nat Commun 12, 3562 (2021).
Method Transformation
Raw sequencing data Relative
Relative abundance Relative
Relative microbiome profiling Relative
Arcsine square root Relative
Centered log ratio Compositional
Absolute count scaling Quantitative