Experimental autoimmune encephalomyelitis

From BugSigDB


An autoimmune demyelinating disease of the central nervous system that is produced experimentally in animals by the injection of homogenized brain or spinal cord in Freund's adjuvant. Myelin basic protein appears to be the antigen that elicits the hypersensitivity immune response which is characterized by focal areas of lymphocyte and macrophage infiltration into the brain, associated with demyelination and destruction of the blood-brain barrier. Experimental allergic encephalomyelitis (EAE) is used as an animal model for demyelinating diseases of the human central nervous system such as multiple sclerosis.
Aliases
  • ALLERGIC ENCEPH
  • ALLERGIC ENCEPH EXPER
  • Allergic encephalomyelitis
  • Allergic encephalomyelitis (disorder)
  • Allergic Encephalomyelitis, Experimental
  • AUTOIMMUNE ENCEPH EXPER
  • Autoimmune Encephalomyelitis, Experimental
  • AUTOIMMUNE EXPER ENCEPH
  • Autoimmune Experimental Encephalomyelitis
  • EAE
  • ENCEPH ALLERGIC
  • ENCEPH AUTOIMMUNE EXPER
  • ENCEPH EXPER AUTOIMMUNE
  • Encephalomyelitis, Allergic
  • Encephalomyelitis, Autoimmune Experimental
  • Encephalomyelitis, Autoimmune, Experimental
  • Encephalomyelitis, Experimental Allergic
  • Encephalomyelitis, Experimental Autoimmune
  • EXPER ALLERGIC ENCEPH
  • EXPER AUTOIMMUNE ENCEPH
  • Experimental Allergic Encephalomyelitides
  • Experimental Allergic Encephalomyelitis
  • Experimental allergic encephalomyelitis (disorder)
  • experimental autoimmune encephalomyelitis
  • Experimental Encephalomyelitis, Autoimmune