Maternal microbiota communicates with the fetus through microbiota-derived extracellular vesicles/Experiment 4

Needs review

Curated date: 2024/03/25

Curator: Iman-Ngwepe

Revision editor(s): Iman-Ngwepe

Host species Species from which microbiome was sampled. Contact us to have more species added.: Homo sapiens

Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology: Amniotic fluid , Feces Acqua amnii,Liquor amnii,Amniotic fluid,amniotic fluid,Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces

Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology: Pregnancy Gestation,PREGN,Pregnancies,Pregnancy,pregnancy

Group 0 name Corresponds to the control (unexposed) group for case-control studies: Amniotic fluid-derived extracellular vesicles (AM EV)

Group 1 name Corresponds to the case (exposed) group for case-control studies: Maternal feces (FE)

Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group: Differences between AM_EV and FE pair

16S variable region One or more hypervariable region(s) of the bacterial 16S gene: V4-V5

Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance: Ion Torrent

Significance threshold p-value or FDR threshold used for differential abundance testing (if any): 0.05

MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?: Yes

Shannon Estimator of species richness and species evenness: more weight on species richness: decreased