The biological effects of microencapsulated organic acids and botanicals induces tissue-specific and dose-dependent changes to the Gallus gallus microbiota/Experiment 5

From BugSigDB


Needs review

Curated date: 2024/03/28

Curator: Omojokunoluwatomisin

Revision editor(s): Omojokunoluwatomisin

Subjects

Location of subjects
United States of America
Host species Species from which microbiome was sampled. Contact us to have more species added.
Gallus gallus
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Jejunum Intestinum jejunum,Mid-intestine,Middle intestine,Jejunum,jejunum
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Chicken feed with 300g/MT
Group 1 name Corresponds to the case (exposed) group for case-control studies
Chickens feed with 500 g/MT
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Chickens that were fed with 500 g/MT of AviPlus®P.
Group 0 sample size Number of subjects in the control (unexposed) group
5
Group 1 sample size Number of subjects in the case (exposed) group
5

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V2
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
centered log-ratio
Statistical test
LEfSe
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No
LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
2

Alpha Diversity

Pielou Quantifies how equal the community is numerically
increased
Shannon Estimator of species richness and species evenness: more weight on species richness
increased

Signature 1

Needs review

Curated date: 2024/03/28

Curator: Omojokunoluwatomisin

Revision editor(s): Omojokunoluwatomisin

Source: Figure 4 and text

Description: Differential abundance of taxa as per the LEfSE analysis.

Abundance in Group 1: increased abundance in Chickens feed with 500 g/MT

NCBI Quality ControlLinks
Clostridiaceae
Micrococcaceae

Revision editor(s): Omojokunoluwatomisin

Signature 2

Needs review

Curated date: 2024/03/28

Curator: Omojokunoluwatomisin

Revision editor(s): Omojokunoluwatomisin

Source: Figure 4 and text

Description: Differential abundance of taxa as per the LEfSE analysis.

Abundance in Group 1: decreased abundance in Chickens feed with 500 g/MT

NCBI Quality ControlLinks
Aerococcaceae

Revision editor(s): Omojokunoluwatomisin