Meta-analysis of effects of exclusive breastfeeding on infant gut microbiota across populations/Experiment 5

From BugSigDB


Reviewed Marked as Reviewed by Peace Sandy on 2024-11-19

Curated date: 2024/10/04

Curator: Shulamite

Revision editor(s): Shulamite

Subjects

Location of subjects
United States of America
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Breastfeeding duration Breastfeeding duration,breastfeeding duration
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Increasing Exclusive Breast Feeding (EBF)
Group 1 name Corresponds to the case (exposed) group for case-control studies
Reduced exclusivity of beast feeding to none breastfeeding
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Exclusive breastfeeding to infants were reduced.
Group 0 sample size Number of subjects in the control (unexposed) group
150
Group 1 sample size Number of subjects in the case (exposed) group
68

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Random Forest Analysis
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.005
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes


Signature 1

Reviewed Marked as Reviewed by Peace Sandy on 2024-11-19

Curated date: 2024/10/04

Curator: Shulamite

Revision editor(s): Shulamite

Source: Table 7

Description: Meta-analysis stratified by mode of delivery for gut bacterial taxa with differential relative abundances between non-exclusively breastfed vs. exclusively breastfed infants ≤6 months of age.

Abundance in Group 1: increased abundance in Reduced exclusivity of beast feeding to none breastfeeding

NCBI Quality ControlLinks
Acidaminococcus
Eubacterium
unclassified Lachnospiraceae
Bacteroides
Erysipelotrichaceae
unclassified Clostridiaceae
Aggregatibacter
Lactococcus
Blautia

Revision editor(s): Shulamite

Signature 3

Reviewed Marked as Reviewed by Peace Sandy on 2024-11-19

Curated date: 2024/10/08

Curator: Shulamite

Revision editor(s): Shulamite, Rahila

Source: Table 7

Description: Meta-analysis stratified by mode of delivery for gut bacterial taxa with differential relative abundances between non-exclusively breastfed vs. exclusively breastfed infants ≤6 months of age.

Abundance in Group 1: decreased abundance in Reduced exclusivity of beast feeding to none breastfeeding

NCBI Quality ControlLinks
Anaerotruncus
Phascolarctobacterium
Proteus
Pseudomonadota
Staphylococcus
unclassified Enterobacteriaceae

Revision editor(s): Shulamite, Rahila