Meta-analysis of effects of exclusive breastfeeding on infant gut microbiota across populations/Experiment 6

From BugSigDB


Reviewed Marked as Reviewed by Peace Sandy on 2024-11-19

Curated date: 2024/10/04

Curator: Shulamite

Revision editor(s): Shulamite

Subjects

Location of subjects
United States of America
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Breastfeeding duration Breastfeeding duration,breastfeeding duration
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Exclusive BreastFeeding (EBF)
Group 1 name Corresponds to the case (exposed) group for case-control studies
Non-Exclusive Breastfeeding (Non-EBF)
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Infants fed with breast milk plus solid or formula.
Group 0 sample size Number of subjects in the control (unexposed) group
38
Group 1 sample size Number of subjects in the case (exposed) group
66

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V3-V5
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Roche454

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.005
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No


Signature 1

Reviewed Marked as Reviewed by Peace Sandy on 2024-11-19

Curated date: 2024/10/04

Curator: Shulamite

Revision editor(s): Shulamite

Source: Table 6

Description: Meta-analysis of six studies without data from VDAART trial study for gut bacterial taxa with differential relative abundances between non-exclusively breastfed vs. exclusively breastfed infants ≤6 months of age (sensitivity analysis).

Abundance in Group 1: increased abundance in Non-Exclusive Breastfeeding (Non-EBF)

NCBI Quality ControlLinks
Acidaminococcus
Bacteroides
Clostridium
Coprococcus
Eubacterium
Megasphaera
Veillonella

Revision editor(s): Shulamite