Role of the Gut Microbiota in the Increased Infant Body Mass Index Induced by Gestational Diabetes Mellitus/Experiment 1
From BugSigDB
Reviewed Marked as Reviewed by Svetlana up on 2024-10-7
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Meconium Meconium,meconium
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Gestational diabetes diabetes in pregnancy,GDM,gestational diabetes,gestational diabetes mellitus,maternal gestational diabetes mellitus,Gestational diabetes
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Healthy controls
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Gestational diabetes mellitus (GDM)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Infants born to women who had gestational diabetes mellitus (GDM)
- Group 0 sample size Number of subjects in the control (unexposed) group
- 60
- Group 1 sample size Number of subjects in the case (exposed) group
- 60
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 months
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- LEfSe
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
- LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
- 2.0
Alpha Diversity
- Richness Number of species
- decreased
Signature 1
Reviewed Marked as Reviewed by Svetlana up on 2024-10-7
Source: FIG 2 (D)
Description: Linear discriminant analysis (LDA) scores for crucial bacteria classification with different abundances in Gestational diabetes mellitus (GDM) versus healthy controls
Abundance in Group 1: increased abundance in Gestational diabetes mellitus (GDM)
| NCBI | Quality Control | Links |
|---|---|---|
| Actinomyces | ||
| Actinomycetaceae | ||
| Actinomycetales | ||
| Cytophaga | ||
| Cytophagaceae | ||
| Xanthobacteraceae | ||
| Yersiniaceae | ||
| Xanthobacter | ||
| Serratia |
Revision editor(s): Rahila
Signature 2
Reviewed Marked as Reviewed by Svetlana up on 2024-10-7
Source: FIG 2 (D)
Description: Linear discriminant analysis (LDA) scores for crucial bacteria classification with different abundances in Gestational diabetes mellitus (GDM) versus healthy controls
Abundance in Group 1: decreased abundance in Gestational diabetes mellitus (GDM)
Revision editor(s): Rahila
