Bacteroides uniformis degrades β-glucan to promote Lactobacillus johnsonii improving indole-3-lactic acid levels in alleviating colitis/Experiment 2

From BugSigDB


Reviewed Marked as Reviewed by Svetlana up on 2024-11-5

Curated date: 2024/10/16

Curator: Appleeyes

Revision editor(s): Appleeyes

Subjects

Location of subjects
China
Host species Species from which microbiome was sampled. Contact us to have more species added.
Mus musculus
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Colitis Colitides,colitis,colitis (disease),colon inflammation,inflammation of colon,Colitis
Group 0 name Corresponds to the control (unexposed) group for case-control studies
0-h fermented samples
Group 1 name Corresponds to the case (exposed) group for case-control studies
24-h fermented samples
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Samples taken 24 hours after the intervention has been administered.
Group 0 sample size Number of subjects in the control (unexposed) group
3
Group 1 sample size Number of subjects in the case (exposed) group
3

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
LEfSe
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes
LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
2


Signature 1

Reviewed Marked as Reviewed by Svetlana up on 2024-11-5

Curated date: 2024/10/25

Curator: Appleeyes

Revision editor(s): Appleeyes

Source: figure 2i

Description: Comparison of relative abundance of bacteria between 0 and 24 h in the fermented sample by LEfSe.

Abundance in Group 1: increased abundance in 24-h fermented samples

NCBI Quality ControlLinks
Allobaculum
Bacilli
Bacteroides
Bacteroides uniformis
Bifidobacteriaceae
Bifidobacterium
Bifidobacterium pseudolongum
Lactobacillaceae
Lactobacillales
Lactobacillus
Parabacteroides
Parabacteroides distasonis

Revision editor(s): Appleeyes

Signature 2

Reviewed Marked as Reviewed by Svetlana up on 2024-11-5

Curated date: 2024/10/25

Curator: Appleeyes

Revision editor(s): Appleeyes

Source: figure 2i

Description: Comparison of relative abundance of bacteria between 0 and 24 h in the fermented sample by LEfSe.

Abundance in Group 1: decreased abundance in 24-h fermented samples

NCBI Quality ControlLinks
Bacteroidales
Bacteroides acidifaciens
Bacteroides ovatus
Bacteroidia
Bilophila
Desulfovibrio
Mucispirillum
Mucispirillum schaedleri
Odoribacter
Streptococcus
Turicibacter
Bacteroidota

Revision editor(s): Appleeyes