Faecal microbiota and cytokine profiles of rural Cambodian infants linked to diet and diarrhoeal episodes/Experiment 2
Subjects
- Location of subjects
- Cambodia
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Diarrhea , Diarrhea, Infantile , Malnutrition Diarrhea,Diarrhoea,Watery stool,diarrhea,Diarrhea, Infantile,diarrhea, Infantile,Lack of food,Malnutrition,malnutrition
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Infants without diarrhea
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Infants with diarrhea
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Infants who experienced diarrhea within the 7 days prior to sample collection.
- Group 0 sample size Number of subjects in the control (unexposed) group
- 26
- Group 1 sample size Number of subjects in the case (exposed) group
- 6
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Statistical test
- MaAsLin2
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.25
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
- Confounders controlled for Confounding factors that have been accounted for by stratification or model adjustment
- time
Signature 1
Source: Figure 2c
Description: Bacterial genera differentially abundant between infants with diarrheal illness and infants without diarrheal illness
Abundance in Group 1: increased abundance in Infants with diarrhea
| NCBI | Quality Control | Links |
|---|---|---|
| Clostridium | ||
| Shigella | ||
| Klebsiella |
Revision editor(s): Aishat
Signature 2
Source: Figure 2c
Description: Bacterial genera differentially abundant between infants with diarrheal illness and infants without diarrheal illness.
Abundance in Group 1: decreased abundance in Infants with diarrhea
| NCBI | Quality Control | Links |
|---|---|---|
| Bacteroides |
Revision editor(s): Aishat
Signature 3
Source: Figure 3c
Description: Bacterial species difference between infants with diarrheal illness and infants without diarrheal illness
Abundance in Group 1: increased abundance in Infants with diarrhea
| NCBI | Quality Control | Links |
|---|---|---|
| Shigella flexneri | ||
| Clostridium perfringens |
Revision editor(s): Aishat
Signature 4
Source: Figure 3c
Description: Bacterial species differentially abundant between infants with diarrheal illness and infants without diarrheal illness.
Abundance in Group 1: increased abundance in Infants with diarrhea
| NCBI | Quality Control | Links |
|---|---|---|
| Shigella flexneri | ||
| Clostridium perfringens |
Revision editor(s): Aishat
