Gut microbiomes of agropastoral children from the Adadle region of Ethiopia reflect their unique dietary habits/Experiment 12

From BugSigDB


Needs review

Curated date: 2024/10/31

Curator: YokoC

Revision editor(s): YokoC

Subjects

Location of subjects
Bangladesh
Cameroon
China
El Salvador
Ethiopia
Malawi
Peru
Sweden
United Republic of Tanzania
United States of America
Venezuela
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Population Population,population
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Cluster P+
Group 1 name Corresponds to the case (exposed) group for case-control studies
Cluster P-
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
One of two clusters based on bacterial taxa abundance, determined by the use of Euclidean distances and Ward's linkage method on data from primer 2 set.
Group 0 sample size Number of subjects in the control (unexposed) group
558
Group 1 sample size Number of subjects in the case (exposed) group
134

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Mann-Whitney (Wilcoxon)
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes


Signature 1

Needs review

Curated date: 2024/10/31

Curator: YokoC

Revision editor(s): YokoC

Source: Figure 3C

Description: Heatmap of the most abundant species with significantly different relative abundance between two clusters (P9+ and P9−) in primer set 2.

Abundance in Group 1: increased abundance in Cluster P-

NCBI Quality ControlLinks
Alloprevotella sp.
Anaerostipes hadrus
Bacteroides fragilis
Bacteroides ovatus
Bacteroides uniformis
Bifidobacterium breve
Bifidobacterium catenulatum
Blautia obeum
Blautia sp.
Dialister invisus
Dialister sp.
Faecalibacterium sp.
Prevotella sp.
Prevotellaceae bacterium
Ruminococcus bromii
Escherichia/Shigella coliEscherichia/Shigella coli
Oscillospiraceae UCG-002 sp.Oscillospiraceae UCG-002 sp.
Fusicatenibacter sp.

Revision editor(s): YokoC

Signature 2

Needs review

Curated date: 2024/11/01

Curator: YokoC

Revision editor(s): YokoC

Source: Figure 3C

Description: Heatmap of the most abundant species with significantly different relative abundance between two clusters (P9+ and P9−) in primer set 2.

Abundance in Group 1: decreased abundance in Cluster P-

NCBI Quality ControlLinks
Prevotella 9 copriPrevotella 9 copri
Succinivibrio sp.

Revision editor(s): YokoC