Gut microbiomes of agropastoral children from the Adadle region of Ethiopia reflect their unique dietary habits/Experiment 16

From BugSigDB


Needs review

Curated date: 2024/11/04

Curator: YokoC

Revision editor(s): YokoC

Subjects

Location of subjects
Ethiopia
Peru
United Republic of Tanzania
Zimbabwe
United States of America
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Population Population,population
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Industrial Lifestyle
Group 1 name Corresponds to the case (exposed) group for case-control studies
Traditional Lifestyle
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
2-5 year old children with a traditional lifestyle, whose samples were taxonomically profiled using mOTUs2.
Group 0 sample size Number of subjects in the control (unexposed) group
29
Group 1 sample size Number of subjects in the case (exposed) group
40

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
log transformation
Statistical test
Mann-Whitney (Wilcoxon)
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes


Signature 1

Needs review

Curated date: 2024/11/04

Curator: YokoC

Revision editor(s): YokoC

Source: Figure S9 B

Description: Significantly different relative abundances of bacterial families in the BloSSUM (Bloom or selected in societies of urbanization/modernization) or VANISH (Volatile and/or associated negatively with industrialized societies of humans) categories and those with higher relative abundance in Adadle woreda.

Abundance in Group 1: increased abundance in Traditional Lifestyle

NCBI Quality ControlLinks
Prevotellaceae
Succinivibrionaceae
Lactobacillaceae

Revision editor(s): YokoC

Signature 2

Needs review

Curated date: 2024/11/04

Curator: YokoC

Revision editor(s): YokoC

Source: Figure S9 B

Description: Significantly different relative abundances of bacterial families in the BloSSUM (Bloom or selected in societies of urbanization/modernization) or VANISH (Volatile and/or associated negatively with industrialized societies of humans) categories and those with higher relative abundance in Adadle woreda.

Abundance in Group 1: decreased abundance in Traditional Lifestyle

NCBI Quality ControlLinks
Akkermansiaceae
Bacteroidaceae
Bifidobacteriaceae

Revision editor(s): YokoC