Differential human gut microbiome assemblages during soil-transmitted helminth infections in Indonesia and Liberia/Experiment 7

From BugSigDB


Needs review

Curated date: 2024/11/02

Curator: KateRasheed

Revision editor(s): KateRasheed

Subjects

Location of subjects
Indonesia
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Helminthiasis helminth infection,helminthiasis,helminthosis,parasitic helminthiasis infectious disease,worm infection,Helminthiasis
Group 0 name Corresponds to the control (unexposed) group for case-control studies
2008 - Uninfected
Group 1 name Corresponds to the case (exposed) group for case-control studies
2010 - Uninfected
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
2010 refers to individuals that were treated with anthelmintics or placebo in 2010, although they were not infected.
Group 0 sample size Number of subjects in the control (unexposed) group
43
Group 1 sample size Number of subjects in the case (exposed) group
32

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V1-V3
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
LEfSe
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes
LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
2


Signature 1

Needs review

Curated date: 2024/11/02

Curator: KateRasheed

Revision editor(s): KateRasheed

Source: Table S5

Description: Differential abundance in the gut microbiota between uninfected individuals in Indonesia (2008-2010), treated with anthelmintics or placebo in 2010.

Abundance in Group 1: increased abundance in 2010 - Uninfected

NCBI Quality ControlLinks
Betaproteobacteria
Burkholderiales
Comamonadaceae

Revision editor(s): KateRasheed

Signature 2

Needs review

Curated date: 2024/11/02

Curator: KateRasheed

Revision editor(s): KateRasheed

Source: Table S5

Description: Differential abundance in the gut microbiota between uninfected individuals in Indonesia (2008-2010), treated with anthelmintics or placebo in 2010.

Abundance in Group 1: decreased abundance in 2010 - Uninfected

NCBI Quality ControlLinks
Afipia
Chryseobacterium
Methylobacteriaceae
Methylobacterium
Nitrobacteraceae
Nocardiaceae
Pedobacter
Pseudomonadaceae
Pseudomonas
Rhizobiaceae
Rhizobium
Rhodococcus
Variovorax

Revision editor(s): KateRasheed