Gut microbiota composition in male rat models under different nutritional status and physical activity and its association with serum leptin and ghrelin levels/Experiment 1
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< Gut microbiota composition in male rat models under different nutritional status and physical activity and its association with serum leptin and ghrelin levels(Redirected from Gut microbiota composition in male rat models under different nutritional status and physical activity and its association with serum leptin and ghrelin levels/Experiment 1)
Reviewed Marked as Reviewed by Shaimaa Elsafoury on 2021/02/09
Subjects
- Location of subjects
- Spain
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Rattus norvegicus
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Physical activity Activities, Locomotor,Activities, Motor,Activities, Physical,Activity, Locomotor,Activity, Motor,Activity, Physical,Locomotor Activities,Locomotor Activity,Motor Activities,Motor Activity,Physical Activities,Physical activity,physical activity
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- exercise group
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Activity Based Anorexia group
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- (a) Activity based anorexia (ABA) group: rats starved by restricting food access to 23 hours per day and confined to running wheels except during a 60 min meal per day, (b) Control ABA group: rats submitted to the same food restriction schedule as ABA with no wheel access exercise, (c) Exercise group: rats feed ad libitum with free access to the activity wheel and (d) Ad libitum group: rats feed ad libitum but without access to the activity wheel.
- Group 0 sample size Number of subjects in the control (unexposed) group
- 10
- Group 1 sample size Number of subjects in the case (exposed) group
- 10
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V2-V3
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- RT-qPCR
Statistical Analysis
- Statistical test
- Kruskall-Wallis
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
- Matched on Factors on which subjects have been matched on in a case-control study
- body weight
Signature 1
Reviewed Marked as Reviewed by Shaimaa Elsafoury on 2021/02/09
Source: Table 3 and Text
Description: Gut microbiota composition in male rat models under different nutritional status and physical activity and its association with serum leptin and ghrelin levels
Abundance in Group 1: increased abundance in Activity Based Anorexia group
| NCBI | Quality Control | Links |
|---|---|---|
| Pseudomonadota | ||
| Prevotella | ||
| Methanobacteriota | ||
| Clostridium | ||
| Enterococcus | ||
| Bacteroides |
Revision editor(s): WikiWorks
Signature 2
Reviewed Marked as Reviewed by Fatima on 2021/08/10
Source: Table 3 and Text
Description: Gut microbiota composition in male rat models under different nutritional status and physical activity and its association with serum leptin and ghrelin levels
Abundance in Group 1: decreased abundance in Activity Based Anorexia group
| NCBI | Quality Control | Links |
|---|---|---|
| Actinomycetota | ||
| Bacteroides | ||
| Bacteroidota | ||
| Bifidobacterium | ||
| Bacillota | ||
| Lactobacillus | ||
| Agathobacter rectalis |
