Microbiota assembly, structure, and dynamics among Tsimane horticulturalists of the Bolivian Amazon/Experiment 1

From BugSigDB


Needs review

Curated date: 2024/11/09

Curator: YokoC

Revision editor(s): YokoC

Subjects

Location of subjects
Bolivia
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Restricted to specific location localized,Restricted to specific location,restricted to specific location
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Proximal River Village
Group 1 name Corresponds to the case (exposed) group for case-control studies
Distal River Village
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Tsimane adults (>14 years old) that live in a village along the Maniqui river, that is more than 20 km away from the regional market and have access to the market via 6-12 hour trips by foot or boat.
Group 0 sample size Number of subjects in the control (unexposed) group
19
Group 1 sample size Number of subjects in the case (exposed) group
77

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
log transformation
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05


Signature 1

Needs review

Curated date: 2024/11/09

Curator: YokoC

Revision editor(s): YokoC

Source: Figure 5C and Sprockett_Tsimane_ps.rds

Description: Discriminatory ASVs for proximal and distal river villages identified using a tree-based LDA algorithm.

Abundance in Group 1: increased abundance in Distal River Village

NCBI Quality ControlLinks
Bacteroides
Bacteroides uniformis
Muribaculaceae
Phocaeicola vulgatus
Bacteroides faecichinchillae/faecis+2Bacteroides faecichinchillae/faecis+2
Bacteroides dorei/fragilisBacteroides dorei/fragilis
Bacteroides fragilis/ovatusBacteroides fragilis/ovatus

Revision editor(s): YokoC

Signature 2

Needs review

Curated date: 2024/11/09

Curator: YokoC

Revision editor(s): YokoC

Source: Figure 5C and Sprockett_Tsimane_ps.rds

Description: Discriminatory ASVs for proximal and distal river villages identified using a tree-based LDA algorithm.

Abundance in Group 1: decreased abundance in Distal River Village

NCBI Quality ControlLinks
Prevotellaceae UCG-003Prevotellaceae UCG-003

Revision editor(s): YokoC