Faecal microbial transfer and complex carbohydrates mediate protection against COPD/Experiment 5
From BugSigDB
Needs review
Subjects
- Location of subjects
- Australia
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Mus musculus
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Response to transplant Response to transplant,response to transplant
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Air-exposed control mice - 8 weeks
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Cigarette Smoke exposed control mice (CS-exposed control mice - 8 weeks)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Cigarette Smoke exposed control mice (CS-exposed control mice - 8 weeks) refers to mice model who received their own soiled bedding mixed with clean bedding for eight weeks.
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V5-V8
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- centered log-ratio
- Statistical test
- PLS-DA (Partial least square discriminant analysis)
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
- Matched on Factors on which subjects have been matched on in a case-control study
- age
Signature 1
Needs review
Source: Figure S7e
Description: Differentially abundant taxa between air-exposed control mice and CS-exposed control mice
Abundance in Group 1: increased abundance in Cigarette Smoke exposed control mice (CS-exposed control mice - 8 weeks)
| NCBI | Quality Control | Links |
|---|---|---|
| Muribaculaceae |
Revision editor(s): KateRasheed
Signature 2
Needs review
Source: Figure S7e
Description: Differentially abundant taxa between air-exposed control mice and CS-exposed control mice at 8weeks.
Abundance in Group 1: decreased abundance in Cigarette Smoke exposed control mice (CS-exposed control mice - 8 weeks)
| NCBI | Quality Control | Links |
|---|---|---|
| Muribaculaceae | ||
| Eubacterium xylanophilum | ||
| Ruminococcus |
Revision editor(s): KateRasheed
