Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn's disease/Experiment 18

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Reviewed Marked as Reviewed by Svetlana up on 2025-1-3

Curated date: 2024/12/18

Curator: Aleru Divine

Revision editor(s): Aleru Divine

Subjects

Location of subjects
Germany
Host species Species from which microbiome was sampled. Contact us to have more species added.
Mus musculus
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Exposure Exposure,exposure
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Unsorted cells
Group 1 name Corresponds to the case (exposed) group for case-control studies
Ethanol (EtOH)
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Model Patient 2 (MP2) samples dissolved in ethanol.

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
ANOVA
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No


Signature 1

Reviewed Marked as Reviewed by Svetlana up on 2025-1-3

Curated date: 2024/12/18

Curator: Aleru Divine

Revision editor(s): Aleru Divine

Source: Figure 2E

Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.

Abundance in Group 1: increased abundance in Ethanol (EtOH)

NCBI Quality ControlLinks
Peptostreptococcus anaerobius

Revision editor(s): Aleru Divine

Signature 2

Needs review

Curated date: 2025/01/02

Curator: Aleru Divine

Revision editor(s): Aleru Divine

Source: Figure 2E

Description: Relative abundances of significantly enriched and depleted zOTUs in MP2.

Abundance in Group 1: decreased abundance in Ethanol (EtOH)

NCBI Quality ControlLinks
[Clostridium] scindens
Thomasclavelia ramosa
Ruthenibacterium lactatiformans
Phocaeicola vulgatus

Revision editor(s): Aleru Divine