Faecal microbiota of schoolchildren is associated with nutritional status and markers of inflammation: a double-blinded cluster-randomized controlled trial using multi-micronutrient fortified rice/Experiment 7
From BugSigDB
Subjects
- Location of subjects
- Cambodia
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Parasitic infection animal parasitic infectious disease,central nervous system parasitic infectious disease,Disease caused by parasite,disease caused by parasite,Disease caused by parasite (disorder),Disease caused by parasite, NOS,Disease, Parasitic,disease, parasitic,Diseases, Parasitic,diseases, parasitic,Ectoparasitic disease,ectoparasitic disease,Infestation,infestation,Infestation, NOS,intestinal parasitism (disorder),intestinal parasitism NOS (disorder),intestinal parasitism, unspecified,intestinal parasitism, unspecified (disorder),Parasite infestation,parasite infestation,Parasite infestation, NOS,parasitemia,parasitic animal,PARASITIC DIS,Parasitic disease,parasitic disease,Parasitic disease, NOS,Parasitic Diseases,parasitic endophthalmitis,Parasitic endophthalmitis (disorder),Parasitic endophthalmitis NOS,Parasitic endophthalmitis NOS (disorder),parasitic eye infection,Parasitic eye infection (disorder),parasitic eye infectious disease,parasitic gastrointestinal disorder,parasitic infection,Parasitic infection of lung,Parasitic infection of skin,Parasitic infection, NOS,parasitic infectious disease,Parasitic infectious disease of the central nervous system (disorder),Parasitic infectious disease, NOS,parasitic infestation of orbit,Parasitic infestation of orbit (disorder),parasitic intestinal infectious disease,parasitic liver disorder,parasitic liver infectious disease,parasitic lung infectious disease,parasitic pregnancy complication,parasitic skin disorder,parasitic skin infectious disease,Parasitic skin infestation (disorder),Parasitism,parasitism,Parasitism, NOS,Parasitosis,parasitosis,Parasitosis, NOS,psorospermiasis,Psorospermiasis (disorder),skin Infestation NOS,Parasitic infection
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- No parasitic infection
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Parasitic infection
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- This group includes children grouped according to parasitic infection
- Group 0 sample size Number of subjects in the control (unexposed) group
- 276
- Group 1 sample size Number of subjects in the case (exposed) group
- 104
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 30 days
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- LEfSe
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
- LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
- 2.0
- Confounders controlled for Confounding factors that have been accounted for by stratification or model adjustment
- age, sex
Alpha Diversity
- Pielou Quantifies how equal the community is numerically
- decreased
- Shannon Estimator of species richness and species evenness: more weight on species richness
- decreased
- Faith Phylogenetic diversity, takes into account phylogenetic distance of all taxa identified in a sample
- decreased
Signature 1
Source: Supplementary Figure 2:
Description: Differential ASVs between the children grouped according to parasite infection,
Abundance in Group 1: increased abundance in Parasitic infection
| NCBI | Quality Control | Links |
|---|---|---|
| Gordonibacter | ||
| Kurthia |
Revision editor(s): Joiejoie
Signature 2
Source: Supplementary Figure 2:
Description: Differential ASVs between the children grouped according to parasite infection,
Abundance in Group 1: decreased abundance in Parasitic infection
| NCBI | Quality Control | Links |
|---|---|---|
| Desulfovibrionaceae | ||
| Holdemanella | ||
| UCG_004UCG_004 | ||
| Erysipelotrichaceae | ||
| Weissella | ||
| Sarcina | ||
| Fastidiosipila | ||
| HungateiclostridiaceaeHungateiclostridiaceae |
Revision editor(s): Joiejoie
