Subgingival Microbial Changes During the First 3 Months of Fixed Appliance Treatment in Female Adult Patients/Experiment 1
From BugSigDB
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Dental plaque Bacterial plaque,Plaque,Dental plaque,dental plaque
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Gingival disease disease of gingiva,disease or disorder of gingiva,disorder of gingiva,gingiva disease,gingiva disease or disorder,gingival disease,Gingival disease
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- before
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- 1 month after the placement of the brackets
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- subgingial microbial changes during fixed appliance treatment
- Group 0 sample size Number of subjects in the control (unexposed) group
- 10
- Group 1 sample size Number of subjects in the case (exposed) group
- 10
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 1 month
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Statistical test
- Metastats
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Chao1 Abundance-based estimator of species richness
- unchanged
- Simpson Estimator of species richness and species evenness: more weight on species evenness
- unchanged
- Inverse Simpson Modification of Simpsons index D as 1/D to obtain high values in datasets of high diversity and vice versa
- unchanged
- Richness Number of species
- unchanged
Signature 1
Needs review
Source: Figure 5
Description: Relative abundance of microbiota that showed statistically significant differences among three different time points
Abundance in Group 1: increased abundance in 1 month after the placement of the brackets
| NCBI | Quality Control | Links |
|---|---|---|
| Actinobacillus | ||
| Capnocytophaga |
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