Early-life gut microbiome composition and milk allergy resolution/Experiment 1
From BugSigDB
Reviewed Marked as Reviewed by Claregrieve1 on 2022/12/28
Subjects
- Location of subjects
- United States of America
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Milk allergic reaction milk allergic reaction,milk allergy,Milk Hypersensitivity,Milk allergic reaction
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- milk allergy resolution
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- children with milk allergy persistence
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- child with persistent milk allergy at age 8
- Group 0 sample size Number of subjects in the control (unexposed) group
- 128
- Group 1 sample size Number of subjects in the case (exposed) group
- 98
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- LEfSe
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
- LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
- 2
Signature 1
Reviewed Marked as Reviewed by Claregrieve1 on 2022/12/28
Source: Figure 1a
Description: Differentially abundant taxa in children with milk allergy persistence versus milk allergy resolution at age 8
Abundance in Group 1: increased abundance in children with milk allergy persistence
| NCBI | Quality Control | Links |
|---|---|---|
| Bacteroidales | ||
| Bacteroidia | ||
| Bacteroidota | ||
| Enterobacter | ||
| Salmonella | ||
| Trabulsiella |
Revision editor(s): Claregrieve1, WikiWorks
Signature 2
Reviewed Marked as Reviewed by Claregrieve1 on 2022/12/28
Source: Figure 1a
Description: Differentially abundant taxa in children with milk allergy persistence versus milk allergy resolution at age 8
Abundance in Group 1: decreased abundance in children with milk allergy persistence
| NCBI | Quality Control | Links |
|---|---|---|
| Blautia | ||
| Clostridia | ||
| Clostridiaceae | ||
| Eubacterium | ||
| Bacillota | ||
| Peptostreptococcaceae | ||
| Prevotellaceae | ||
| Ruminococcus |
Revision editor(s): Claregrieve1, WikiWorks
