Different gastric microbiota compositions in two human populations with high and low gastric cancer risk in Colombia/Experiment 1

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Reviewed Marked as Reviewed by Claregrieve1 on 2022/09/1

Curated date: 2021/01/10

Curator: WikiWorks

Revision editor(s): Claregrieve1, WikiWorks

Subjects

Location of subjects
Colombia
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Stomach Anterior intestine,Gaster,Mesenteron,Stomach chamber,Ventriculus,Stomach,stomach
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Gastric cancer Ca body - stomach,ca greater curvature of stomach,Ca lesser curvature - stomach,cancer of stomach,gastric cancer,gastric cancer, intestinal,gastric neoplasm,malignant gastric neoplasm,malignant gastric tumor,malignant neoplasm of body of stomach,malignant neoplasm of lesser curve of stomach,malignant neoplasm of stomach,malignant neoplasm of the stomach,malignant stomach neoplasm,malignant tumor of body of stomach,malignant tumor of greater curve of stomach,malignant tumor of lesser curve of stomach,malignant tumor of stomach,malignant tumor of the stomach,stomach cancer,Gastric cancer
Group 0 name Corresponds to the control (unexposed) group for case-control studies
low gastric cancer risk patients (Tumaco residents)
Group 1 name Corresponds to the case (exposed) group for case-control studies
high gastric cancer risk patients (Tuquerres residents)
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
individuals from Tuquerres with high gastric cancer risk
Group 0 sample size Number of subjects in the control (unexposed) group
20
Group 1 sample size Number of subjects in the case (exposed) group
20
Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
30 days

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Statistical test
Metastats
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes
Matched on Factors on which subjects have been matched on in a case-control study
age, sex


Signature 1

Reviewed Marked as Reviewed by Claregrieve1 on 2022/09/1

Curated date: 2021/01/10

Curator: Valentina Pineda

Revision editor(s): Claregrieve1, WikiWorks

Source: Table 3

Description: Differential microbial abundance between Tuquerres and Tumaco residents

Abundance in Group 1: increased abundance in high gastric cancer risk patients (Tuquerres residents)

NCBI Quality ControlLinks
Leptotrichia wadei
Veillonella sp.

Revision editor(s): Claregrieve1, WikiWorks

Signature 2

Reviewed Marked as Reviewed by Claregrieve1 on 2022/09/1

Curated date: 2021/01/10

Curator: Valentina Pineda

Revision editor(s): WikiWorks, Lwaldron, Claregrieve1, Merit

Source: Table 3

Description: Differential microbial abundance between Tuquerres and Tumaco residents

Abundance in Group 1: decreased abundance in high gastric cancer risk patients (Tuquerres residents)

NCBI Quality ControlLinks
Actinomyces sp.
Capnocytophaga gingivalis
Flavobacteriaceae
Flavobacterium sp.
Neisseria flavescens
Neisseria sp.
Porphyromonadaceae
Porphyromonas sp.
Segatella oris
Rothia sp. (in: high G+C Gram-positive bacteria)
Sphingomonadaceae
Staphylococcus sp.
Streptococcus oralis
uncultured Haematobacter sp.

Revision editor(s): WikiWorks, Lwaldron, Claregrieve1, Merit