Association Between Gut Microbiota and Helicobacter pylori-Related Gastric Lesions in a High-Risk Population of Gastric Cancer/Experiment 5

From BugSigDB


Reviewed Marked as Reviewed by Claregrieve1 on 2022/07/20

Curated date: 2021/01/10

Curator: WikiWorks

Revision editor(s): Rimsha, Claregrieve1, WikiWorks

Subjects

Location of subjects
China
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Gastric cancer Ca body - stomach,ca greater curvature of stomach,Ca lesser curvature - stomach,cancer of stomach,gastric cancer,gastric cancer, intestinal,gastric neoplasm,malignant gastric neoplasm,malignant gastric tumor,malignant neoplasm of body of stomach,malignant neoplasm of lesser curve of stomach,malignant neoplasm of stomach,malignant neoplasm of the stomach,malignant stomach neoplasm,malignant tumor of body of stomach,malignant tumor of greater curve of stomach,malignant tumor of lesser curve of stomach,malignant tumor of stomach,malignant tumor of the stomach,stomach cancer,Gastric cancer
Group 0 name Corresponds to the control (unexposed) group for case-control studies
normal
Group 1 name Corresponds to the case (exposed) group for case-control studies
subjects with metaplasia
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
subjects with metaplasia
Group 0 sample size Number of subjects in the control (unexposed) group
7
Group 1 sample size Number of subjects in the case (exposed) group
22

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Statistical test
Welch's T-Test
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No

Alpha Diversity

Shannon Estimator of species richness and species evenness: more weight on species richness
unchanged
Richness Number of species
unchanged

Signature 1

Reviewed Marked as Reviewed by Claregrieve1 on 2022/07/20

Curated date: 2021/01/10

Curator: Fatima Zohra

Revision editor(s): Claregrieve1, WikiWorks, Merit

Source: Figure 4

Description: differential microbial abundance between subjects with metaplasia and normal subjects

Abundance in Group 1: increased abundance in subjects with metaplasia

NCBI Quality ControlLinks
Bacillota
Clostridia
Dialister
Dorea
Enterobacterales
Enterobacteriaceae
Erysipelotrichaceae
Erysipelotrichales
Erysipelotrichia
Eubacteriales
Eubacterium coprostanoligenes
Lachnoclostridium
Gammaproteobacteria
Lachnospiraceae
Peptostreptococcaceae
Pseudomonadota
Romboutsia
Turicibacter
Clostridiaceae
Clostridiales bacterium

Revision editor(s): Claregrieve1, WikiWorks, Merit

Signature 2

Reviewed Marked as Reviewed by Claregrieve1 on 2022/07/20

Curated date: 2021/01/10

Curator: Fatima Zohra

Revision editor(s): Claregrieve1, WikiWorks

Source: Figure 4

Description: differential microbial abundance between subjects with metaplasia and normal subjects

Abundance in Group 1: decreased abundance in subjects with metaplasia

NCBI Quality ControlLinks
Bacteroidales
Bacteroidota
Bacteroidia

Revision editor(s): Claregrieve1, WikiWorks