Understanding the microbial basis of body odor in pre-pubescent children and teenagers
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Quality control
- Retracted paper
- Contamination issues suspected
- Batch effect issues suspected
- Uncontrolled confounding suspected
- Results are suspect (various reasons)
- Tags applied
Experiment 1
Subjects
- Location of subjects
- Philippines
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Skin of body Entire integument,Entire skin,Integument,Integumental organ,Pelt,Skin,Skin organ,Skin of body
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- body odor measurement body odour measurement,body odor measurement
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- head of child
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- head of teen-ager
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Malodor is a phenotype that is well known to arise from specific interactions between host-derived odor precursors and the microbial metabolism that they support
- Group 0 sample size Number of subjects in the control (unexposed) group
- 15
- Group 1 sample size Number of subjects in the case (exposed) group
- 15
Lab analysis
- Sequencing type
- WMS
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Statistical test
- Mann-Whitney (Wilcoxon)
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Signature 1
Source: Figure S3, S4
Description: Identification of significant microbial genera and species associated with different body sites i.e(head, neck and underarm).
Abundance in Group 1: increased abundance in head of teen-ager
NCBI | Quality Control | Links |
---|---|---|
Cutibacterium | ||
Cutibacterium acnes |
Signature 2
Source: Figure S3, S4
Description: Identification of significant microbial genera and species associated with different body sites, i.e, (head, neck and underarm)
Abundance in Group 1: decreased abundance in head of teen-ager
NCBI | Quality Control | Links |
---|---|---|
Malassezia | ||
Malassezia globosa | ||
Staphylococcus | ||
Staphylococcus epidermidis | ||
Staphylococcus hominis |
Experiment 2
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- child neck
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- teen neck
Lab analysis
Statistical Analysis
Signature 1
Source: Figure S3, S4
Description: Identification of significant microbial genera and species associated with different body sites (head, neck and underarm)
Abundance in Group 1: increased abundance in teen neck
NCBI | Quality Control | Links |
---|---|---|
Cutibacterium | ||
Malassezia | ||
Cutibacterium acnes | ||
Malassezia globosa |
Revision editor(s): WikiWorks
Signature 2
Source: Figure S3, S4
Description: Identification of significant microbial genera and species associated with different body sites (head, neck and underarm)
Abundance in Group 1: decreased abundance in teen neck
NCBI | Quality Control | Links |
---|---|---|
Staphylococcus | ||
Staphylococcus hominis |
Revision editor(s): WikiWorks
Experiment 3
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- child underarm
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- teen underarm
Lab analysis
Statistical Analysis
Signature 1
Source: Figure S3, S4
Description: Identification of significant microbial genera and species associated with different body sites (head, neck and underarm)
Abundance in Group 1: increased abundance in teen underarm
NCBI | Quality Control | Links |
---|---|---|
Staphylococcus epidermidis | ||
Malassezia globosa |
Revision editor(s): WikiWorks
Signature 2
Source: Figure S3, S4
Description: Identification of significant microbial genera and species associated with different body sites (head, neck and underarm)
Abundance in Group 1: decreased abundance in teen underarm
NCBI | Quality Control | Links |
---|---|---|
Staphylococcus hominis |
Revision editor(s): WikiWorks