Understanding the microbial basis of body odor in pre-pubescent children and teenagers/Experiment 1

From BugSigDB


Reviewed Marked as Reviewed by Shaimaa Elsafoury on 2021/02/09

Curated date: 2021/01/10

Curator: WikiWorks

Revision editor(s): WikiWorks, Davvve, ChiomaBlessing

Subjects

Location of subjects
Philippines
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Skin of body Entire integument,Entire skin,Integument,Integumental organ,Pelt,Skin,Skin organ,Skin of body,skin of body
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Body odor measurement body odour measurement,Body odor measurement,body odor measurement
Group 0 name Corresponds to the control (unexposed) group for case-control studies
head of child
Group 1 name Corresponds to the case (exposed) group for case-control studies
head of teenager
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Malodor is a phenotype that is well known to arise from specific interactions between host-derived odor precursors and the microbial metabolism that they support
Group 0 sample size Number of subjects in the control (unexposed) group
15
Group 1 sample size Number of subjects in the case (exposed) group
15

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Mann-Whitney (Wilcoxon)
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes


Signature 1

Reviewed Marked as Reviewed by Shaimaa Elsafoury on 2021/02/09

Curated date: 2021/01/10

Curator: Rimsha Azhar

Revision editor(s): WikiWorks, Davvve, ChiomaBlessing

Source: Figure S3, S4

Description: Significant microbial genera and species associated with teen head VS child head

Abundance in Group 1: increased abundance in head of teenager

NCBI Quality ControlLinks
Cutibacterium
Cutibacterium acnes

Revision editor(s): WikiWorks, Davvve, ChiomaBlessing

Signature 2

Reviewed Marked as Reviewed by Shaimaa Elsafoury on 2021/02/09

Curated date: 2021/01/10

Curator: Rimsha Azhar

Revision editor(s): WikiWorks, Davvve, ChiomaBlessing

Source: Figure S3, S4

Description: Significant microbial genera and species associated with teen head VS child head

Abundance in Group 1: decreased abundance in head of teenager

NCBI Quality ControlLinks
Malassezia
Malassezia globosa
Staphylococcus
Staphylococcus epidermidis
Staphylococcus hominis

Revision editor(s): WikiWorks, Davvve, ChiomaBlessing