Understanding the microbial basis of body odor in pre-pubescent children and teenagers/Experiment 1

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Reviewed Marked as Reviewed by Shaimaa Elsafoury on 2021/02/09

Curated date: 2021/01/10

Curator: WikiWorks

Revision editor(s): WikiWorks, Davvve, ChiomaBlessing

Subjects

Location of subjects

Philippines

Host species Species from which microbiome was sampled. Contact us to have more species added.

Homo sapiens

Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology

Skin of body Entire integument,Entire skin,Integument,Integumental organ,Pelt,Skin,Skin organ,Skin of body,skin of body

Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology

Body odor measurement body odour measurement,Body odor measurement,body odor measurement

Group 0 name Corresponds to the control (unexposed) group for case-control studies

head of child

Group 1 name Corresponds to the case (exposed) group for case-control studies

head of teenager

Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group

Malodor is a phenotype that is well known to arise from specific interactions between host-derived odor precursors and the microbial metabolism that they support

Group 0 sample size Number of subjects in the control (unexposed) group

15

Group 1 sample size Number of subjects in the case (exposed) group

15

Lab analysis

Sequencing type

WMS

16S variable region One or more hypervariable region(s) of the bacterial 16S gene

Not specified

Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance

Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).

relative abundances

Statistical test

Mann-Whitney (Wilcoxon)

Significance threshold p-value or FDR threshold used for differential abundance testing (if any)

0.05

MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?

Yes

Signature 1

EditHistoryDelete

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Your review change was submitted

Reviewed Marked as Reviewed by Shaimaa Elsafoury on 2021/02/09

Curated date: 2021/01/10

Curator: Rimsha Azhar

Revision editor(s): WikiWorks, Davvve, ChiomaBlessing

Source: Figure S3, S4

Description: Significant microbial genera and species associated with teen head VS child head

Abundance in Group 1: increased abundance in head of teenager

NCBI	Quality Control	Links
Cutibacterium
Cutibacterium acnes

Revision editor(s): WikiWorks, Davvve, ChiomaBlessing

Signature 2

EditHistoryDelete

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Your review change was submitted

Reviewed Marked as Reviewed by Shaimaa Elsafoury on 2021/02/09

Curated date: 2021/01/10

Curator: Rimsha Azhar

Revision editor(s): WikiWorks, Davvve, ChiomaBlessing

Source: Figure S3, S4

Description: Significant microbial genera and species associated with teen head VS child head

Abundance in Group 1: decreased abundance in head of teenager

NCBI	Quality Control	Links
Malassezia
Malassezia globosa
Staphylococcus
Staphylococcus epidermidis
Staphylococcus hominis

Revision editor(s): WikiWorks, Davvve, ChiomaBlessing